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B7-H2: Antibodies

Human B7-H2, also called B7RP-1, B7h, LICOS, and GL50, is a member of the growing B7 family of immune costimulatory proteins. Other family members include B7-1, B7-2, B7-H1 (PD-L1), PD-L2, and B7-H3. B7 proteins are members of the immunoglobulin (Ig) superfamily, the extracellular domains contain 2 Ig-like domains and all members have short cytoplasmic domains. Among the family members, they share about 20-25% amino acid identity. Human and mouse B7-H2 share approximately 49% amino acid identity.

B7-H2 has been identified as the ligand for ICOS, a member of the CD28 family of costimulatory receptors. Human B7-H2 is a 309 amino acid (aa) protein with a putative 18 aa signal peptide, a 239 aa extracellular domain, an 18 aa transmembrane region, and a 33 aa cytoplasmic domain. Human B7-H2 is expressed constitutively on resting B cells, dendritic cells, and at low levels on monocytes. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and T Helper (Th) cell differentiation.

40 results for "B7-H2 Primary Antibodies" in Products

B7-H2: Antibodies

Human B7-H2, also called B7RP-1, B7h, LICOS, and GL50, is a member of the growing B7 family of immune costimulatory proteins. Other family members include B7-1, B7-2, B7-H1 (PD-L1), PD-L2, and B7-H3. B7 proteins are members of the immunoglobulin (Ig) superfamily, the extracellular domains contain 2 Ig-like domains and all members have short cytoplasmic domains. Among the family members, they share about 20-25% amino acid identity. Human and mouse B7-H2 share approximately 49% amino acid identity.

B7-H2 has been identified as the ligand for ICOS, a member of the CD28 family of costimulatory receptors. Human B7-H2 is a 309 amino acid (aa) protein with a putative 18 aa signal peptide, a 239 aa extracellular domain, an 18 aa transmembrane region, and a 33 aa cytoplasmic domain. Human B7-H2 is expressed constitutively on resting B cells, dendritic cells, and at low levels on monocytes. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and T Helper (Th) cell differentiation.

40 results for "B7-H2 Primary Antibodies" in Products

Flow, CyTOF-ready, Neut
WB, Flow, CyTOF-ready
Flow, Block, CyTOF-ready, Neut
Flow, CyTOF-ready, ICC
Catalog #: FAB165N
Flow
WB, ICC
Flow, Block, CyTOF-ready
WB, Flow
WB, Neut
Catalog #: FAB165V
Flow
Catalog #: FAB165G
Flow
Catalog #: BAF158
WB
Catalog #: FAB10083T
Flow
Catalog #: FAB158V
Flow
Catalog #: FAB158N
Flow
Catalog #: FAB1582U
Flow
Catalog #: FAB165T
Flow
Catalog #: FAB1582T
Flow
Catalog #: FAB165S
Flow
Catalog #: FAB1582N
Flow
Catalog #: FAB1582G
Flow
Catalog #: FAB158G
Flow
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