Skip to main content

11 results for "3C and 3CL Protease Inhibitors" in Products

3C and 3CL Protease Inhibitors Products

3C and 3C-like proteases are cysteine proteases identified in coronaviruses and picornaviruses, such as SARS-CoV, poliovirus and rhinovirus. The active form of these proteases is dimeric, with each monomer contributing a cysteine-histidine catalytic domain to the active site. The individual monomers are inactive without dimerization. 3C and 3CL proteases are essential to the life cycle of the virus, and are key to the proteolytic processing of polyproteins that are translated from viral RNA by ...

Show More

Proteasome and calpain inhibitor. Inhibits NF-κB activation

Alternate Names: Z-LLL-al,Z-Leu-Leu-Leu-CHO
Chemical Name: N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-L-leucinamide
Purity: ≥95% (HPLC)
Proteasome and calpain inhibitor. Inhibits NF-κB activation

Non-selective PI 3-kinase inhibitor

Chemical Name: 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one
Purity: ≥98% (HPLC)
Non-selective PI 3-kinase inhibitor

Coronavirus Mpro inhibitor

Chemical Name: tert-Butyl (1-((S)-1-(((S)-4-(benzylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-3-cyclopropyl-1-oxopropan-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)carbamate
Purity: ≥97% (HPLC)
Coronavirus Mpro inhibitor

Coronavirus Mpro inhibitor

Chemical Name: N-[(5-Methyl-3-isoxazolyl)carbonyl]-L-alanyl-L-valyl-N-[(1S,2E)-4-oxo-1-[[(3S)-2-oxo-3-pyrrolidinyl]methyl]-4-(phenylmethoxy)-2-buten-1-yl]-L-leucinamide
Purity: ≥98% (HPLC)
Coronavirus Mpro inhibitor

Potent non-covalent inhibitor of SARS-CoV-2 main protease

Chemical Name: 5-[5-[3-Chloro-5-[(2-chlorophenyl)methoxy]-4-fluorophenyl]-6-oxo[1(6H),3'-bipyridin]-3-yl]-1-methyl-2,4(1H,3H)-pyrimidinedione
Purity: ≥95% (HPLC)
Potent non-covalent inhibitor of SARS-CoV-2 main protease

Reversibly stimulates SERCA Ca2+-ATPase; displays a range of other activities

Alternate Names: Tetraethylthiuram disulfide
Chemical Name: Bis(diethylthiocarbamyoyl)disulfide
Reversibly stimulates SERCA Ca2+-ATPase; displays a range of other activities

Potent hepatitis C virus (HCV) NS3 protease inihibitor

Chemical Name: 1-[[N-tert-Butoxycarbonyl-L-tert-leucyl-trans-4-[(7-chloro-4-methoxyisoquinolin-1-yl)oxy]-L-prolyl]amino]-N-(cyclopropylsulfonyl)-(1R,2S)-2-vinylcyclopropane-1-carboxamide
Purity: ≥98% (HPLC)
Potent hepatitis C virus (HCV) NS3 protease inihibitor

Potent colony-stimulating factor 1 receptor (CSF-1R) tyroine kinase inhibitor

Chemical Name: 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide
Purity: ≥98% (HPLC)
Potent colony-stimulating factor 1 receptor (CSF-1R) tyroine kinase inhibitor

Negative control for Mpro 13b-K (Cat. No. 7228)

Chemical Name: tert-Butyl (1-((R)-1-(((S)-4-(benzylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-3-cyclopropyl-1-oxopropan-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)carbamate
Purity: ≥97% (HPLC)
Negative control for Mpro 13b-K (Cat. No. 7228)

Glutathione peroxidase mimic; peroxynitrite scavenger

Chemical Name: 2-Phenyl-1,2-benzisoselenazol-3(2H)-one
Purity: ≥98% (HPLC)
Glutathione peroxidase mimic; peroxynitrite scavenger

SARS-CoV-2 Mpro Degrader (PROTAC®)

Chemical Name: 3-((6-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)hexyl)oxy)benzyl ((2S,3R)-3-(tert-butoxy)-1-(((S)-3-cyclohexyl-1-oxo-1-(((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)amino)propan-2-yl)amino)-1-oxobutan-2-yl)carbamate
Application of MPD 2
(2)
Results Per Page
5 10 25 50
/ 1