CE-SDS with Maurice
Meet Maurice, your fully automated CE platform that gives you:
- Ease of use
- Reproducibility
- High-quality data
- Easy method transfer
- Regulatory compliance
Table of Contents

Implement CE-SDS at Any Stage of Biotherapeutic Development
Turbo CE-SDS™ - high quality size analysis in as little as 5.5 minutes for high-throughput applications including cell culture and clonal selection
CE-SDS PLUS - fast method development, high-quality data, and seamless method transfer to QC
Analyze Different Types of Molecules
Get purity data under 35 minutes for all sorts of biotherapeutics – mAbs, biosimilars, viral vectors, GMP proteins, and more. See our Additional Resources for information.


Transition From SDS-PAGE to CE-SDS
Say goodbye cumbersome and manual SDS-PAGE – no more preparing gels, laborious sample prep, and poor reproducibility. With CE-SDS, you’ll get high quality, quantitative, and reproducible data. You can even get a gel-like representation of your data using Lane View on the Compass for iCE software. Maurice even comes with an optional filtration upgrade for containing those noxious β-ME odors.
Here are some more resources to help you with your transition:
- Comparing SDS-PAGE with Maurice CE-SDS – this application note demonstrates the many advantages of CE-SDS in direct comparison to SDS-PAGE.
- Apparent Molecular Weight on CE-SDS and SDS-PAGE – this Technical Note highlights relevant peer-reviewed publications addressing factors for comparing molecular weights between CE-SDS and SDS-PAGE.
- A comparative study of CE-SDS, SDS-PAGE, and Simple Western – this publication from the University of Braunschweig focuses on sample preparation and MW marker selection and their impact on apparent molecular weight.
Advantages of CE-SDS over SDS-PAGE
The accurate and quantitative analysis of product purity is a fundamental component of effective development of a biotherapeutic protein. Without consistent techniques and high-quality, reproducible results, it is difficult to precisely assess the product's efficacy and/or safety, potentially delaying, even jeopardizing, its approval. Hear about the advantages of automated CE-SDS on Maurice over manual SDS-PAGE by listening to our Podcast with Drug Discovery World (DDW) and Dr. Tufan Aydogdu, Field Applications Scientist, ProteinSimple, a Bio-Techne brand.

Reduce Time in the Lab
From generating USP <129> comparable data to allowing control with the Waters™ Empower® software, Maurice enhances CE-SDS and saves you time and resources!
- Get USP <129> Equivalent Data with Maurice CE-SDS – this Application Note demonstrates the comparability of the Maurice CE-SDS PLUS method with the USP <129> protocol for the analysis of monoclonal antibodies.
- QC-Specific Workflows Made Easy – this Application Note shows you how to develop a QC-specific workflow that eliminates the need to use a commercial internal standard, freeing you from concerns like introducing contaminants to test samples that might interfere with subsequent analyses.
- Power up Maurice with Waters™ Empower® Software – this Application Note explains how Maurice gives you the data integrity, repeatability, and accuracy you need in your regulated laboratory environment by allowing a seamless integration with the Waters Empower 3 software.
- Easily Transfer Your CE-SDS Methods to Maurice – this webinar explains how scientists from Pfizer optimized their Maurice CE-SDS method to achieve comparable results to those of a conventional CE system.
Additional Resources
-
Develop Your Biosimilars Faster - White Paper on Maurice CE-SDS for ICH Q6B Based Biosimilar Comparability Exercises
-
Maurice vs PA 800/PA 800 Plus - Application Note comparing the CE-SDS analysis of a NIST mAb using Maurice and PA 800 systems
-
Automate your AAV Characterization Using Low Sample Volumes - Application Note on Using CE-SDS for AAV purity analysis
-
Save Time and Money with Maurice for QC - White Paper on Streamlining the CE-SDS Workflow
-
Maurice vs LabChip - Application note evaluating CE-SDS separation using a reference NIST mAb on Maurice and the LabChip® GXII Touch