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Accelerate Your Cetuximab Biosimilar Development

by ProteinSimple, a Bio-Techne brand.

Application Notes

Application Notes Summary

In this study, both charge and molecular weight heterogeneity of Cetuximab were evaluated under eight different conditions — high temperature (accelerated and stress condition), freeze-thaw cycles, agitation, low pH, high pH, exposure to light (photostability), oxidation, and glycation. The goal of this study is to demonstrate how protein charge and size heterogeneity analysis from a single instrument for stability studies can be used as guidance in biosimilar stability design.

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