Mouse IL-6R alpha Antibody
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Species Reactivity: | Mouse |
Immunogen: |
Mouse myeloma cell line NS0-derived recombinant mouse IL-6R alpha Leu20-Glu357 Accession # P22272 |
Applications: | Block/Neutralize, CyTOF-ready, ELISA Capture, Flow Cytometry, Immunohistochemistry, Western Blot |
Label: | Unconjugated |
Source: | Polyclonal Goat IgG |
Specificity: |
Detects mouse IL-6R alpha in ELISAs and Western blots. In sandwich ELISAs, less than 0.3% cross-reactivity with recombinant mouse (rm) IL‑6, recombinant human IL-6 R and rmgp130 is observed. |
Complete Your Research
Complete Your Experiment
Citations for Mouse IL-6R alpha Antibody (15)
Citations are publications that use Bio-Techne products. Selected citations for Mouse IL-6R alpha Antibody include:
-
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCA Shimada et al. (2021), Increased cytokine expression in the choroid plexus stroma and epithelium in response to endotoxin-induced systemic inflammation in mice Toxicology reports, 8(0):520-528.
PMID: 33747797 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCD Zhao et al. (2020), Chromatin Regulator, CHD1, Remodels the Immunosuppressive Tumor Microenvironment in PTEN-Deficient Prostate Cancer Cancer Discov, 0(0).
PMID: 32385075 -
Species: Mouse
Sample Types: In Vivo
Applications: NeutralizationM Zhou et al. (2020), Extracellular CIRP induces macrophage endotoxin tolerance through IL-6R-mediated STAT3 activation JCI Insight, 0(0).
PMID: 32027619 -
Species: Human
Sample Types: Protein Lysates
Applications: Western BlotH Huang et al. (2019), Targeting TGFbetaR2-mutant tumors exposes vulnerabilities to stromal TGFbeta blockade in pancreatic cancer EMBO Mol Med, 0(0):e10515.
PMID: 31609088 -
Species: Mouse
Sample Types: Transduced Whole Cells
Applications: NeutralizationSM Kim et al. (2019), Role of Proinflammatory Cytokines in Feedback Modulation of Circadian Clock Gene Rhythms by Saturated Fatty Acids Sci Rep, 9(1):8909.
PMID: 31222133 -
Species: Mouse
Sample Types: Whole Cells
Applications: NeutralizationAJ St Leger et al. (2018), STAT-3-independent production of IL-17 by mouse innate-like ?? T cells controls ocular infection J. Exp. Med., 0(0).
PMID: 29490936 -
Species: Mouse
Sample Types: In Vivo
Applications: NeutralizationX Wang et al. (2017), Rapid monocyte infiltration following retinal detachment is dependent on non-canonical IL6 signaling through gp130 J Neuroinflammation, 14(1):121.
PMID: 28645275 -
P Arnold et al. (2017), Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling Sci Rep, 7(0):44053.
PMID: 28276471 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNana Owusu-Boai (2016), Macrophagic control of the response to uropathogenic E. coli infection by regulation of iron retention in an IL-6-dependent manner Immun Inflamm Dis, 4(4):413-426.
PMID: 27980776 -
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western BlotGarbers C et al. (2011), Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding. J. Biol. Chem., 286(17):14804-11.
PMID: 21454673 -
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western BlotWalker F et al. (2007), IL6/sIL6R complex contributes to emergency granulopoietic responses in G-CSF- and GM-CSF-deficient mice. Blood, 111(8):3978-85.
PMID: 18156493 -
Species: Mouse
Sample Types: Air Pouch Exudate
Applications: ELISA DevelopmentRabe B et al. (2007), Transgenic blockade of interleukin 6 transsignaling abrogates inflammation. Blood, 111(3):1021-8.
PMID: 17989316 -
Species: Mouse
Sample Types: Lavage Fluid
Applications: ELISA DevelopmentChalaris A et al. (2007), Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils. Blood, 110(6):1748-55.
PMID: 17567983 -
Species: Mouse
Applications: NeutralizationKurooka M et al. (2007), Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells. Cancer Res., 67(1):227-36.
PMID: 17210703 -
Species: Mouse
Sample Types: Plasma
Applications: ELISA DevelopmentOsuchowski MF et al. (2005), Sequential ELISA to profile multiple cytokines from small volumes. J. Immunol. Methods, 302(1):172-81.
PMID: 16023134
There are no citations that match your criteria.