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246 results for "ubiquitin-ligase-e3-inhibitors&view=expanded" in Products

Reactivity:
Human, Mouse, Hamster
Details:
Rabbit IgG Polyclonal
Applications:
KO, IHC, WB, ICC/IF, IP
Western Blot: HRD1 AntibodyBSA Free [NB100-2526]
(4)

Negative control for VH 298

Chemical Name:
(2S,4S)-1-((S)-2-(1-cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity:
≥98%
Negative control for VH 298

CHIP/STUB1 E3 ligase inhibitor

Purity:
≥95%
CHIP/STUB1 E3 ligase inhibitor

SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase

Chemical Name:
N-(4-Butyl-2-methylphenyl)acetamide
Purity:
≥98%
SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase

Cdc20 inhibitor; inhibits Cdc20-substrate interaction

Chemical Name:
3-(2-Methyl-5-nitroimidazol-1-yl)-N-(2,2,2-trichloro-1-phenylaminoethyl)propionamide
Purity:
≥98%
Cdc20 inhibitor; inhibits Cdc20-substrate interaction

Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase

Chemical Name:
3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
Purity:
≥98%
Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase

β-TrCP1 ligase inhibitor

Chemical Name:
4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid
Purity:
≥98%
β-TrCP1 ligase inhibitor

Cereblon binder; also TNF-α inhibitor and antiangiogenic

Chemical Name:
4-Amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
Purity:
≥98%
Cereblon binder; also TNF-α inhibitor and antiangiogenic

Selective inhibitor of E3 ubiquitin ligase

Chemical Name:
9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one
Purity:
≥98%
Selective inhibitor of E3 ubiquitin ligase

Potent, selective and reversible DCN1-UBC12 interaction inhibitor

Chemical Name:
5-[[2-[[(4-Chlorophenyl)methyl]thio]-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]thio]-N,N-dimethyl-1H-tetrazole-1-ethanamine hydrochloride
Purity:
≥98%
Potent, selective and reversible DCN1-UBC12 interaction inhibitor
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