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6 results for "TOP2A Small Molecules and Peptides" in Products

TOP2A: Small Molecules and Peptides

Topo II Alpha encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of ...

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Antitumor antibiotic agent. Inhibits DNA topoisomerase II

Alternate Names: Adriamycin,NSC 123127
Chemical Name: 10-[(3-Amino-2,3,6-trideoxy-α-L-lyxohexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-5,12-naphthacenedione hydrochloride
Purity: ≥98% (HPLC)
Doxorubicin treated cardiomyocytes secrete Troponin T
(3)

Topoisomerase II inhibitor

Chemical Name: [5R-[5α,5aβ,8aα,9β(R*)]]-9-[(4,6-Ο-Ethylidene-β-D-glucopyranosyl)oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6-(5aH)-one
Purity: ≥98% (HPLC)
Topoisomerase II inhibitor

DNA topoisomerase inhibitor

Chemical Name: (S)-4-Ethyl-4-hydroxy-1H-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Purity: ≥98% (HPLC)
DNA topoisomerase inhibitor

DNA topoisomerase II inhibitor

Alternate Names: Daunomycin
Chemical Name: (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyransoyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione hydrochloride
Purity: ≥98% (HPLC)
DNA topoisomerase II inhibitor

Antibiotic; inhibits bacterial DNA synthesis

Alternate Names: CP 99219
Chemical Name: 7-[(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid mesylate
Purity: ≥98% (HPLC)
Antibiotic; inhibits bacterial DNA synthesis

Topoisomerase II inhibitor

Alternate Names: ICRF-187
Chemical Name: 4-[(2S)-2-(3,5-Dioxopiperazin-1-yl)propyl]piperazine-2,6-dione hydrochloride
Purity: ≥98% (HPLC)
Topoisomerase II inhibitor
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