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208 results for "SHP-1" in Products

SHP-1 Products

The SH2 domain-containing phosphatases, SHP-1 and SHP-2, are well-studied cytosolic tyrosine phosphatases that share many structural and regulatory features. They both have two tandem SH2 domains at the N-terminus, followed by a catalytic domain, and an inhibitory C-terminus. Despite their structural similarity, the enzymes appear to have different physiological roles and exhibit different expression patterns. SHP-1 is highly expressed in hematopoietic tissues, and in general has a negative impact on lymphocyte signaling. In contrast, SHP-2 is widely expressed, and in general promotes signaling pathways that lead to differentiation, cell growth, or migration.

Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies

The Human Phospho-Immunoreceptor Array detects multiple tyrosine phosphorylated immunoreceptors in lysates prepared from cells activated by antibody mediated cross-linking of cell-surface immunoreceptors.
(2)

Protein tyrosine phosphatase inhibitor

Chemical Name: Trisodium vanadate
Protein tyrosine phosphatase inhibitor
Reactivity: Human
Details: Rat IgG2a Monoclonal Clone #255402
Source: E. coli
Accession #: P29350
Applications: EnzAct
R&D Systems Recombinant Proteins and Enzymes

Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #SR41-02
Applications: IHC, WB, ICC/IF, Flow, IP
Western Blot: SHP-1 Antibody (SR41-02) [NBP2-67321]
(10)
Reactivity: Human, Mouse, Rat
Details: Goat IgG Polyclonal
Reactivity: Human, Mouse, Rat
Details: Goat IgG Polyclonal
Reactivity: Human, Mouse, Rat
Details: Goat IgG Polyclonal
Reactivity: Human, Mouse, Rat
Details: Goat IgG Polyclonal
Reactivity: Human, Mouse, Rat
Details: Goat IgG Polyclonal
Reactivity: Human, Mouse, Rat
Details: Goat IgG Polyclonal
Reactivity: Human
Details: Mouse IgG1 kappa Monoclonal Clone #PTPN6/7543
Applications: IHC
SHP-1 Antibody (PTPN6/7543)
(2)
Reactivity: Human
Details: Rat IgG2a Monoclonal Clone #255402
Reactivity: Human
Details: Rat IgG2a Monoclonal Clone #255402
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