Sodium orthovanadate
Tocris Bioscience, part of Bio-Techne | Catalog # 2821
Protein tyrosine phosphatase inhibitor
Key Product Details
Description
Protein tyrosine phosphatase inhibitor
Product Description
Sodium orthovanadate is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and ATPases. Suppresses p53-mediated apoptosis by transcription-dependent and -independent pathways.Product Specifications
Molecular Weight
183.91
Formula
Na3O4V
Storage
Store at RT
Chemical Name
Trisodium vanadate
CAS Number
13721-39-6
PubChem ID
61671
InChI Key
IHIXIJGXTJIKRB-UHFFFAOYSA-N
SMILES
O=[V]([O-])([O-])[O-].[Na+].[Na+].[Na+]
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 18.39 | 100 |
Preparing Stock Solutions
for Sodium orthovanadate
The following data is based on the product molecular weight 183.91
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 5.44 mL | 27.19 mL | 54.37 mL |
| 5 mM | 1.09 mL | 5.44 mL | 10.87 mL |
| 10 mM | 0.54 mL | 2.72 mL | 5.44 mL |
| 50 mM | 0.11 mL | 0.54 mL | 1.09 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Morita Sodium orthovanadate inhibits p53-mediated apoptosis. Cancer Res. 2010 PMID: 20048077
- Hasegawa Therapeutic time window and dose dependence of neuroprotective effects of sodium orthovanadate following transient middle cerebral artery occlusion in rats. J.Pharmacol.Exp.Ther. 2006 PMID: 16461588
- Matsumoto Sodium orthovanadate enhances proliferation of progenitor cells in the adult rat subventricular zone after focal cerebral ischemia. J.Pharmacol.Exp.Ther. 2006 PMID: 16782823
- Ai Inhibition of small-intestinal sugar absorption mediated by sodium orthovanadate Na3VO4 in rats and its mechanisms. World J.Gastroenterol. 2004 PMID: 15534916
Product Specific Notices for Sodium orthovanadate
For research use only
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