5 results for "RIPK2/RIP2 Small Molecules and Peptides" in Products
RIPK2/RIP2: Small Molecules and Peptides
RIPK2 encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.
Potent RIPK2 inhibitor
| Chemical Name: | 3-(Benzoylamino)-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]benzamide |
| Purity: | ≥98% (HPLC) |
Selective inhibitor of p38 MAPK
| Alternate Names: | Adezmapimod |
| Chemical Name: | 4-[5-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]pyridine |
| Purity: | ≥98% (HPLC) |
Potent RIPK2 inhibitor; orally bioavailable and cell permeable
| Chemical Name: | 6-[(1,1-Dimethylethyl)sulfonyl]-N-(5-fluoro-1H-indazol-3-yl)-4-quinolinamine |
| Purity: | ≥98% (HPLC) |
RIPK2 modulator; pro-drug of cRIPGM; orally bioavailable and brain penetrant
| Chemical Name: | N-[1,4-Dihydro-1,4-dioxo-3-[(phenylmethyl)amino]-2-naphthalenyl]-N-[(4-fluorophenyl)methyl]acetamide |
| Purity: | ≥98% (HPLC) |
Selective inhibitor of p38 MAPK; water-soluble
| Chemical Name: | 4-[5-(4-Fluorophenyl)-2-[4-(methylsulphonyl)phenyl]-1H-imidazol-4-yl]pyridine hydrochloride |
| Purity: | ≥98% (HPLC) |
