11 results for "Retinoic Acid Receptor Agonists" in Products
Retinoic Acid Receptor Agonists Products
Retinoic acid receptors (RARs) are nuclear hormone receptors of the NR1B class, which function as heterodimers with retinoid X receptors (RXRs). There are three distinct RAR subtypes: RARα, RARβ and RARγ. RARα is present in most tissue types, whereas RARβ and RARγ expression is more selective.
RXR-RAR heterodimers act as ligand-dependent transcriptional regulators by binding to the specific retinoic acid response element (RARE) found in the promoter regions of ...
Endogenous retinoic acid receptor agonist
| Alternate Names: | Tretinoin,ATRA |
| Chemical Name: | 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid |
| Purity: | ≥98% (HPLC) |
Retinoic acid synthesized to Ancillary Material Grade
| Chemical Name: | 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E-nonatetraenoic acid |
| Purity: | ≥98% |
Retinoic acid analog; RARα agonist
| Chemical Name: | 4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carboxamido]benzoic acid |
| Purity: | ≥98% (HPLC) |
Retinoic acid analog; RAR agonist
| Alternate Names: | Ro 13-7410 |
| Chemical Name: | 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid |
| Purity: | ≥98% (HPLC) |
RARα agonist; anticancer agent
| Alternate Names: | Tamibarotene |
| Chemical Name: | 4-[[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)amino]carbonyl]benzoic acid |
| Purity: | ≥98% (HPLC) |
RARα-selective agonist
| Chemical Name: | 4-[[(2,3-Dihydro-1,1,3,3-tetramethyl-2-oxo-1H-inden-5-yl)carbonyl]amino]benzoic acid |
| Purity: | ≥98% (HPLC) |
Potent and selective RARγ agonist
| Chemical Name: | 4-(6-Hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic acid |
| Purity: | ≥98% (HPLC) |
Potent RAR agonist
| Chemical Name: | 4-[(1E)-3-[3,5-bis(1,1-Dimethylethyl)phenyl]-3-oxo-1-propenyl]benzoic acid |
| Purity: | ≥98% (HPLC) |
Selective RARβ agonist
| Chemical Name: | 5-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)-3-thiophenecarboxylic acid |
| Purity: | ≥98% (HPLC) |
Selective RARγ agonist
| Chemical Name: | 3-Fluoro-4-[[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8,-tetrahydro-2-naphthalenyl)acetyl]amino]-benzoic acid |
| Purity: | ≥95% (HPLC) |
RARβ2 agonist
| Chemical Name: | 4-[4-(2-Butoxyethoxy-)-5-methyl-2-thiazolyl]-2-fluorobenzoic acid |
| Purity: | ≥98% (HPLC) |
