CD 1530

Name: CD 1530
Brand: Tocris Bioscience
SKU: 2554

Catalog # 2554 | Tocris Bioscience a Bio-Techne Brand

Citations (3)

COA / SDS

Potent and selective RARγ agonist

Key Product Details

Description:	Potent and selective RARγ agonist
Chemical Name:	4-(6-Hydroxy-7-tricyclo[3.3.1.1^3,7]dec-1-yl-2-naphthalenyl)benzoic acid
Purity:	≥98% (HPLC)
Molecular Weight:	398.49

View Full Technical Details for CD 1530

Technical Data
Citations (3) / Reviews

Biological Activity for CD 1530

CD 1530 is a potent and selective RARγ receptor agonist (K_i values are 150, 1500 and 2750 nM for RARγ, RARβ and RARα receptors respectively). Activates transcriptional activity (AC₅₀ = 1.8 nM).

Compound Libraries for CD 1530

CD 1530 is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for CD 1530

M. Wt	398.49
Formula	C₂₇H₂₆O₃
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	107430-66-0
PubChem ID	24868309
InChi Key	VCQGNUWOMLYNNG-UHFFFAOYSA-N
Smiles	OC(C(C1(C[C@@H]2C3)C[C@H](C2)C[C@H]3C1)=C4)=CC5=C4C=C(C6=CC=C(C(O)=O)C=C6)C=C5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for CD 1530

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	39.84	100

Preparing Stock Solutions for CD 1530

The following data is based on the product molecular weight 398.49.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.51 mL	12.55 mL	25.09 mL
5 mM	0.50 mL	2.51 mL	5.02 mL
10 mM	0.25 mL	1.25 mL	2.51 mL
50 mM	0.05 mL	0.25 mL	0.50 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for CD 1530

References are publications that support the biological activity of the product.

Thacher Therapeutic applications for ligands of retinoid receptors. Curr.Pharmaceut.Des.

Citations for CD 1530 (3)

Showing 1 - 3 of 3 citations Showing All

Search Title:

Citations are publications that use Bio-Techne products. Selected citations for CD 1530 include:

Nguyen et al. (2017) Retinoic acid receptor regulation of epimorphic and homeostatic regeneration in the axolotl. Development. 144:601
PMID: 28087637
Duprey-Díaz et al. (2016) Exogenous Modulation of Retinoic Acid Signaling Affects Adult RGC Survival in the Frog Visual System afterOptic Nerve Injury PLoS One. 11:e0162626
PMID: 27611191
Garnaas et al. (2012) Rargb regulates organ laterality in a zebrafish model of right atrial isomerism. Dev Biol. 372:178
PMID: 22982668

There are no citations that match your criteria.