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Ret Products
The GDNF family members (GDNF, neurturin, artemin, and persephin) signal through multicomponent receptors that consist of the Ret receptor tyrosine kinase and one of four glycosyl-phosphatidylinositol (GPI)-linked ligand-binding subunits (GFR alpha-1-4). GFR alpha-1, -2, -3 and -4 are the preferred ligand-binding subunits for GDNF, neurturin, artemin, and persephin, respectively. The Ret tyrosine-kinase receptor is encoded by the c-ret proto-oncogene. Human and mouse Ret share 83% amino acid sequence homology.
29 results for "Ret" in Products
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Ret Products
The GDNF family members (GDNF, neurturin, artemin, and persephin) signal through multicomponent receptors that consist of the Ret receptor tyrosine kinase and one of four glycosyl-phosphatidylinositol (GPI)-linked ligand-binding subunits (GFR alpha-1-4). GFR alpha-1, -2, -3 and -4 are the preferred ligand-binding subunits for GDNF, neurturin, artemin, and persephin, respectively. The Ret tyrosine-kinase receptor is encoded by the c-ret proto-oncogene. Human and mouse Ret share 83% amino acid sequence homology.
29 results for "Ret" in Products
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Western Blot |
| Source : | NS0 |
| Accession # : | P07949 |
| Applications : | Bioactivity |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | Western Blot |
| Source : | NS0 |
| Accession # : | P07949 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #132507 |
| Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
| Source : | NS0 |
| Accession # : | P35546.2 |
| Applications : | Binding Activity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #132507 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #132507 |
| Applications : | Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG1 Clone #64623 |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #132507 |
| Applications : | Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #132507 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #132507 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #132507 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #132507 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #132507 |
| Applications : | Flow Cytometry |
Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
| Alternate Names : | Semaxinib |
| Chemical Name : | 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one |
| Purity : | ≥99% (HPLC) |
Potent and selective RET inhibitor
| Chemical Name : | 6-(2-Hydroxy-2-methylpropoxy)-4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]hept-3-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile |
| Purity : | ≥98% (HPLC) |
