9 results for "Protease-Activated Receptor Agonists Small Molecules and Peptides" in Products
Protease-Activated Receptor Agonists: Small Molecules and Peptides
Protease-activated receptors (PARs, also known as thrombin receptors) are G-protein-coupled receptors, activated by cleavage of their N-terminal domains by serine proteases. Hydrolysis reveals a tethered peptide ligand, which interacts with the receptor within extracellular loop-2 to affect transmembrane signaling. Four subtypes of receptors have so far been cloned (PAR1-4).
PAR1 is the most well characterized member of this receptor family and is activated by the endogenous serine protease ...
Causes platelet aggregation and secretion
| Alternate Names: | TRAP |
| Purity: | ≥95% (HPLC) |
PAR1 peptide fragment (residues 42-47); acts as a PAR1 agonist
| Alternate Names: | Thrombin receptor activator peptide 6 |
| Purity: | ≥95% (HPLC) |
PAR2 receptor agonist
| Purity: | ≥95% (HPLC) |
PAR2 receptor agonist
| Chemical Name: | (±)-(3R*,4S*)-2-Oxo-4-phenyl-3-pyrollidinecarboxylic acid 2-[1-(3-bromophenyl)ethylidene]hydrazide |
| Purity: | ≥98% (HPLC) |
Potent and selective PAR2 agonist
| Purity: | ≥95% (HPLC) |
Selective PAR4 agonist
| Alternate Names: | AYPGKF-NH2 |
| Purity: | ≥95% (HPLC) |
PAR1-activating peptide
| Purity: | ≥95% (HPLC) |
PAR2-activating peptide
| Purity: | ≥95% (HPLC) |
PAR3 peptide agonist
| Purity: | ≥95% (HPLC) |
