PKC zeta Products
Protein kinase C-zeta (EC=2.7.11.13), also called PKC2, is a 79 kDa member of the atypical PKC (aPKC) subfamily of Ser/Thr protein kinases. aPKC proteins can be activated by phorbol esters, but are insensitive to calcium and diacylglycerol. PKC zeta regulates cell polarity in early development and is necessary for cytokine-induced chemotaxis of macrophages and cancer cells, chemokine-induced adhesion of neutrophils, polarization of Th2 cells, and regulation of adherens and tight junction formation.
7 results for "PKC zeta" in Products
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PKC zeta Products
Protein kinase C-zeta (EC=2.7.11.13), also called PKC2, is a 79 kDa member of the atypical PKC (aPKC) subfamily of Ser/Thr protein kinases. aPKC proteins can be activated by phorbol esters, but are insensitive to calcium and diacylglycerol. PKC zeta regulates cell polarity in early development and is necessary for cytokine-induced chemotaxis of macrophages and cancer cells, chemokine-induced adhesion of neutrophils, polarization of Th2 cells, and regulation of adherens and tight junction formation.
7 results for "PKC zeta" in Products
Clonality : | Polyclonal |
Host : | Sheep IgG |
Applications : | Knockout Validated, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #453513 |
Applications : | Western Blot |
Clonality : | Polyclonal |
Host : | Sheep IgG |
Applications : | Immunohistochemistry, Western Blot |
Non-selective protein kinase inhibitor
Alternate Names : | AM-2282 |
Chemical Name : | [9S-(9α,10β,11β,13α)]-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one |
Purity : | ≥98% (HPLC) |
PKCι and PKCζ inhibitor
Chemical Name : | (2S)-3-Phenyl-N1-[5,6,7,8-tetrahydro-2-(4-pyridinyl)[1]benzothieno[2,3-d]pyrimidin-4-yl]-1,2-propanediamine dihydrochloride |
Purity : | ≥95% (HPLC) |
Protein kinase C inhibitor
Alternate Names : | Gö 6850, Bisindolylmaleimide I |
Chemical Name : | 2-[1-(3-Dimethylaminopropyl)indol-3-yl]-3-(indol-3-yl) maleimide |
Purity : | ≥98% (HPLC) |
Protein kinase inhibitor
Alternate Names : | SF 2370 |
Chemical Name : | (9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester |
Purity : | ≥98% (HPLC) |