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186 results for "PDGF-AA" in Products

PDGF-AA Products

PDGF-AA (Platelet-Derived Growth Factor AA) is a widely expressed protein that forms disulfide linked homodimers or heterodimers with PDGF-B. PDGF-AA is expressed by monocytes, macrophages, fibroblasts, vascular smooth muscle cells, and vascular endothelial cells. It acts principally as a chemoattractant and inducer of protein synthesis in multiple cell types. PDGF-AA binds and signals through homodimers of the receptor tyrosine kinase PDGF R alpha which itself associates with FGF R1 and Neuropilin-1. PDGF-AA additionally signals through heterodimers of PDGF R alpha and PDGF R beta.

Reactivity:
Human
Assay Range:
15.6-1000 pg/mL
Applications:
ELISA
Human PDGF-AA ELISA Standard Curve
GMP Version Available: 221-GMP
GMP
Reactivity:
Human
Source:
E. coli
Accession #:
P04085
Applications:
Bioactivity
Graph showing bioactivity of PDGF-AA ability to induce NR6R-3T3 mouse fibroblast cell proliferation
(2)

Animal-Free

Reactivity:
Human
Source:
E. coli
Accession #:
P04085.1
Applications:
Bioactivity
Recombinant Human PDGF-AA GMP Protein Bioactivity
(2)
Reactivity:
Rat
Assay Range:
31.2-2000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)
Applications:
ELISA
Rat IL-2 ELISA Standard Curve
(2)

Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies

Reactivity:
Human
Profiling Angiogenesis-Related Proteins in Human Cancer Tissues.
(3)
Reactivity:
Rat
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, B/N
Reactivity:
Rat
Source:
E. coli
Accession #:
AAB59693.1
Applications:
Bioactivity
R&D Systems Recombinant Proteins and Enzymes
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, B/N
Cell Proliferation Induced by PDGF‑AA and Neutralization by Human PDGF‑AA Antibody.
(3)
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, B/N
Cell Proliferation Induced by PDGF‑AA and Neutralization by Human PDGF‑AA Antibody.
(2)
Reactivity:
Rat
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, B/N
Cell Proliferation Induced by PDGF‑AA and Neutralization by Rat PDGF‑AA Antibody.
Reactivity:
Rat
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, B/N
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
WB, B/N
Cell Proliferation Induced by PDGF and Neutralization by Human PDGF Antibody.
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #114506
Applications:
B/N
Cell Proliferation Induced by PDGF‑AA and Neutralization by Human PDGF‑AA Antibody.
Reactivity:
Multi-Species
Details:
Goat IgG Polyclonal
Applications:
WB, B/N
Cell Proliferation Induced by PDGF and Neutralization by PDGF Antibody.
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #114503
Applications:
WB
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, ELISA(Det)
Human PDGF-AB ELISA Standard Curve
Reactivity:
Rat
Details:
Mouse IgG2B Monoclonal Clone #184805
Applications:
WB
Reactivity:
Human
Source:
CHO
Accession #:
NP_001382295.1
Applications:
Bioactivity
(2)

Intended for preclinical researchers who may transition to GMP PDGF-AA for their clinical work

GMP Version Available: 221-GMP
GMP
Reactivity:
Human
Source:
E. coli
Accession #:
P04085.1
Applications:
Bioactivity
R&D Systems Animal-Free Recombinant Proteins
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