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7 results for "Nav1.6 Small Molecules and Peptides" in Products

Nav1.6: Small Molecules and Peptides

Voltage-dependent sodium channels, such as SCN8A, are responsible for the initial membrane depolarization that occurs during generation of action potentials in most electrically excitable cells (Plummer et al., 1998 [PubMed 9828131]).[supplied by OMIM]

Potent hNav1.4, rNav1.6 and rNav1.7 channel activator

Purity: ≥95% (HPLC)
Potent hNav1.4, rNav1.6 and rNav1.7 channel activator

Cardiac Na+ channel blocker. Antiarrhythmic

Chemical Name: N-(2-Piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzamide acetate
Purity: ≥98% (HPLC)
Cardiac Na+ channel blocker. Antiarrhythmic

Antianginal, activates pyruvate dehydrogenase

Alternate Names: RS 43285
Chemical Name: N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide dihydrochloride
Purity: ≥98% (HPLC)
Antianginal, activates pyruvate dehydrogenase

NaV blocker; neuroprotective

Alternate Names: 619C89
Chemical Name: 2-(4-Methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-4-pyrimidinamine
Purity: ≥98% (HPLC)
NaV blocker; neuroprotective

Inhibitor of neuronal NaV channels; anticonvulsant

Alternate Names: CBZ
Chemical Name: 5H-Dibenz[b,f]azepine-5-carboxamide
Purity: ≥98% (HPLC)
Inhibitor of neuronal NaV channels; anticonvulsant

Na+ channel blocker; antiarrhythmic agent

Alternate Names: Ko 1173
Chemical Name: 1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride
Purity: ≥98% (HPLC)
Na+ channel blocker; antiarrhythmic agent

Blocks voltage-sensitive Na+ and Ca2+ channels (T-type)

Alternate Names: AD 810,CI 912
Chemical Name: 1,2-Benzisoxazole-3-methanesulfonamide
Purity: ≥99% (HPLC)
Blocks voltage-sensitive Na+ and Ca2+ channels (T-type)
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