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5 results for "MIF Small Molecules and Peptides" in Products

MIF: Small Molecules and Peptides

MIF (macrophage migration inhibitory factor) is a pro-inflammatory cytokine that is released during microbial infection, ARDS, rheumatoid arthritis, atherosclerosis, type 2 diabetes, and cancer. It signals through CXCR4, CXCR7, or complexes of CD74-CD44. MIF exhibits potent paracrine and autocrine stimulatory effects on cell growth and survival and enhances the production of inflammatory cytokines. It also inhibits the effectiveness of immunosuppressive glucocorticoids.

Inhibitor of macrophage migration inhibitory factor (MIF); suicide substrate

Chemical Name: 4-Iodo-6-phenylpyrimidine
Purity: ≥98% (HPLC)
Inhibitor of macrophage migration inhibitory factor (MIF); suicide substrate

Potent MIF Degrader (PROTAC®)

Chemical Name: 8-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-N-(4-(7-hydroxy-2-oxo-2H-benzo[e][1,3]oxazin-3(4H)-yl)phenyl)octanamide
Purity: ≥98% (HPLC)
Potent MIF Degrader (PROTAC®)

Macrophage migration inhibitory factor (MIF) inhibitor

Chemical Name: 4,5-Dihydro-3-(4-hydroxyphenyl)-5-isoxazoleacetic acid methyl ester
Purity: ≥98% (HPLC)
Macrophage migration inhibitory factor (MIF) inhibitor

MIF binder

Chemical Name: 2-(2-Pyridinyl)-4H-1,3-benzothiazin-4-one
Purity: ≥98% (HPLC)
MIF binder

Negative control for MD13 (Cat. No. 7503)

Chemical Name: N-(4-(7-Hydroxy-2-oxo-2H-benzo[e][1,3]oxazin-3(4H)-yl)phenyl)-8-((2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)octanamide
Purity: ≥98% (HPLC)
Negative control for MD13 (Cat. No. 7503)
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