MIF: Small Molecules and Peptides
MIF (macrophage migration inhibitory factor) is a pro-inflammatory cytokine that is released during microbial infection, ARDS, rheumatoid arthritis, atherosclerosis, type 2 diabetes, and cancer. It signals through CXCR4, CXCR7, or complexes of CD74-CD44. MIF exhibits potent paracrine and autocrine stimulatory effects on cell growth and survival and enhances the production of inflammatory cytokines. It also inhibits the effectiveness of immunosuppressive glucocorticoids.
5 results for "MIF Small Molecules and Peptides" in Products
5 results for "MIF Small Molecules and Peptides" in Products
MIF: Small Molecules and Peptides
MIF (macrophage migration inhibitory factor) is a pro-inflammatory cytokine that is released during microbial infection, ARDS, rheumatoid arthritis, atherosclerosis, type 2 diabetes, and cancer. It signals through CXCR4, CXCR7, or complexes of CD74-CD44. MIF exhibits potent paracrine and autocrine stimulatory effects on cell growth and survival and enhances the production of inflammatory cytokines. It also inhibits the effectiveness of immunosuppressive glucocorticoids.
Macrophage migration inhibitory factor (MIF) inhibitor
| Chemical Name: | 4,5-Dihydro-3-(4-hydroxyphenyl)-5-isoxazoleacetic acid methyl ester |
| Purity: | ≥98% (HPLC) |
Inhibitor of macrophage migration inhibitory factor (MIF); suicide substrate
| Chemical Name: | 4-Iodo-6-phenylpyrimidine |
| Purity: | ≥98% (HPLC) |
Potent MIF Degrader (PROTAC®)
| Chemical Name: | 8-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-N-(4-(7-hydroxy-2-oxo-2H-benzo[e][1,3]oxazin-3(4H)-yl)phenyl)octanamide |
| Purity: | ≥98% (HPLC) |
MIF binder
| Chemical Name: | 2-(2-Pyridinyl)-4H-1,3-benzothiazin-4-one |
| Purity: | ≥98% (HPLC) |
Negative control for MD13 (Cat. No. 7503)
| Chemical Name: | N-(4-(7-Hydroxy-2-oxo-2H-benzo[e][1,3]oxazin-3(4H)-yl)phenyl)-8-((2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)octanamide |
| Purity: | ≥98% (HPLC) |
