LDLR Products
LDLR (Low Density Lipoprotein Receptor) is a widely expressed cell surface scavenger receptor. LDLR binds ApoB and ApoE, the apolipoproteins of low- and very low-density lipoproteins (LDL and VLDL), respectively. Hepatocyte LDLR is responsible for endocytosis and clearing of most plasma LDL cholesterol. At the low pH of the endocytic vesicle, it dissociates, allowing degradation of LDL and recycling of LDLR to the cell surface. Lack of LDLR expression or function causes familial hypercholesterolemia (FH). The protease PCSK9 can also cause increased plasma cholesterol by promoting LDLR degradation rather than recycling to the cell surface.
Products:
381 results for "LDLR" in Products
381 results for "LDLR" in Products
LDLR Products
LDLR (Low Density Lipoprotein Receptor) is a widely expressed cell surface scavenger receptor. LDLR binds ApoB and ApoE, the apolipoproteins of low- and very low-density lipoproteins (LDL and VLDL), respectively. Hepatocyte LDLR is responsible for endocytosis and clearing of most plasma LDL cholesterol. At the low pH of the endocytic vesicle, it dissociates, allowing degradation of LDL and recycling of LDLR to the cell surface. Lack of LDLR expression or function causes familial hypercholesterolemia (FH). The protease PCSK9 can also cause increased plasma cholesterol by promoting LDLR degradation rather than recycling to the cell surface.
Products:
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Block, ICC |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, IHC, Block, CyTOF-ready |
| Reactivity: | Human, Mouse, Rat, Bovine, Porcine |
| Details: | Mouse IgG2B Monoclonal Clone #C7 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +3 More |
![Western Blot: LDLR Antibody (C7) [NBP1-78159]](https://resources.bio-techne.com/images/products/LDL-R-Antibody-C7-Western-Blot-NBP1-78159-img0008.jpg "Western Blot: LDLR Antibody (C7) [NBP1-78159]")
| Sensitivity: | 10.3 pg/mL |
| Applications: | ELISA |
| Assay Range: | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, Heparin Plasma, Urine) |
| Source: | NS0 |
| Accession #: | P01130 |
| Applications: | BA |
| Sensitivity: | 0.064 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.313 - 20 ng/mL (Cell Culture Supernates, Tissue Homogenates, Serum, EDTA Plasma, Heparin Plasma) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #472413 |
| Applications: | WB, Flow, IP, CyTOF-ready |
| Reactivity: | Human, Mouse, Canine, Bovine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Func, KO, +1 More |
![Knockout Validated: LDLR Antibody - BSA Free [NBP1-06709]](https://resources.bio-techne.com/images/products/LDLR-Antibody-Knockout-Validated-NBP1-06709-img0009.jpg "Western Blot: LDLR Antibody - BSA Free [NBP1-06709]")
| Source: | NS0 |
| Accession #: | Q59FQ1 |
| Applications: | Bind |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #472413 |
| Applications: | Flow |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Human, Rat, Bovine, Porcine |
| Details: | Mouse IgG2B Monoclonal Clone #C7 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +3 More |
![Western Blot: LDLR Antibody (C7)Azide and BSA Free [NBP2-80833]](https://resources.bio-techne.com/images/products/LDLR-Antibody-C7-Azide-and-BSA-Free-Western-Blot-NBP2-80833-img0001.jpg "Western Blot: LDLR Antibody (C7)Azide and BSA Free [NBP2-80833]")
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #263123 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #472413 |
| Applications: | Flow |
| Source: | HEK293 |
| Accession #: | XP_005588053.1 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, IHC, Block, CyTOF-ready |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, IHC, ICC |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #SJ0197 |
| Applications: | IHC, WB, ICC/IF, Flow |
![Western Blot: LDLR Antibody (SJ0197) [NBP2-67414]](https://resources.bio-techne.com/images/products/LDLR-Antibody-SJ0197-Western-Blot-NBP2-67414-img0008.jpg "Western Blot: LDLR Antibody (SJ0197) [NBP2-67414]")
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #263123 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Block, ICC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Block, ICC |