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411 results for "LDLR" in Products
LDLR Products
LDLR (Low Density Lipoprotein Receptor) is a widely expressed cell surface scavenger receptor. LDLR binds ApoB and ApoE, the apolipoproteins of low- and very low-density lipoproteins (LDL and VLDL), respectively. Hepatocyte LDLR is responsible for endocytosis and clearing of most plasma LDL cholesterol. At the low pH of the endocytic vesicle, it dissociates, allowing degradation of LDL and recycling of LDLR to the cell surface. Lack of LDLR expression or function causes familial hypercholesterolemia (FH). The protease PCSK9 can also cause increased plasma cholesterol by promoting LDLR degradation rather than recycling to the cell surface.
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, B/N, Flow, CyTOF-ready
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, B/N, ICC/IF
Reactivity:
Human, Rat, Porcine, Bovine
Details:
Mouse IgG2B Monoclonal Clone #C7
Applications:
IHC, WB, ELISA, Flow, ICC/IF, + 3 More
![Western Blot: LDLR Antibody (C7) [NBP1-78159]](https://resources.rndsystems.com/images/products/LDL-R-Antibody-C7-Western-Blot-NBP1-78159-img0008.jpg "Western Blot: LDLR Antibody (C7) [NBP1-78159]")
Reactivity:
Human, Mouse, Bovine, Canine
Details:
Rabbit IgG Polyclonal
Applications:
KO, IHC, WB, ICC/IF, Simple Western
![Knockout Validated: LDLR Antibody - BSA Free [NBP1-06709]](https://resources.rndsystems.com/images/products/LDLR-Antibody-Knockout-Validated-NBP1-06709-img0009.jpg "Western Blot: LDLR Antibody - BSA Free [NBP1-06709]")
Reactivity:
Human
Assay Range:
62.5-4000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, Heparin Plasma, Urine)
Applications:
ELISA
Reactivity:
Mouse
Assay Range:
0.313-20 ng/mL (Cell Culture Supernates, Tissue Homogenates, Serum, EDTA Plasma, Heparin Plasma)
Applications:
ELISA
Reactivity:
Human
Source:
NS0
Accession #:
P01130
Applications:
Bioactivity
Reactivity:
Human
Source:
NS0
Accession #:
Q59FQ1
Applications:
Binding Activity
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #472413
Applications:
WB, ELISA(Cap), Flow, IP, CyTOF-ready
Reactivity:
Human, Rat, Porcine, Bovine
Details:
Mouse IgG2B Monoclonal Clone #C7
Applications:
IHC, WB, ELISA, Flow, ICC/IF, + 3 More
![Western Blot: LDLR Antibody (C7)Azide and BSA Free [NBP2-80833]](https://resources.rndsystems.com/images/products/LDLR-Antibody-C7-Azide-and-BSA-Free-Western-Blot-NBP2-80833-img0001.jpg "Western Blot: LDLR Antibody (C7)Azide and BSA Free [NBP2-80833]")
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #472413
Applications:
Flow
Reactivity:
Human, Mouse
Details:
Rabbit IgG Monoclonal Clone #SJ0197
Applications:
IHC, WB, Flow, ICC/IF
![Western Blot: LDLR Antibody (SJ0197) [NBP2-67414]](https://resources.rndsystems.com/images/products/LDLR-Antibody-SJ0197-Western-Blot-NBP2-67414-img0008.jpg "Western Blot: LDLR Antibody (SJ0197) [NBP2-67414]")
Reactivity:
Human
Assay Range:
125-8000 pg/mL
Applications:
ELISA
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #263123
Applications:
WB, Flow, CyTOF-ready
Reactivity:
Rat
Assay Range:
0.31 - 20 ng/mL
Applications:
ELISA
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #472413
Applications:
Flow
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #1B10H10
Applications:
IHC, WB, ELISA, Flow, CyTOF-ready
![Western Blot: LDLR Antibody (1B10H10)BSA Free [NBP2-52502]](https://resources.rndsystems.com/images/products/LDL-R-Antibody-1B10H10-Western-Blot-NBP2-52502-img0003.jpg "Western Blot: LDLR Antibody (1B10H10)BSA Free [NBP2-52502]")
Reactivity:
Human
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, Flow, ICC/IF
Reactivity:
Mouse
Source:
NS0
Accession #:
NP_034830
Applications:
Binding Activity
Reactivity:
Mouse
Assay Range:
62.5-4000 pg/mL
Applications:
ELISA
Reactivity:
Cynomolgus Monkey
Source:
HEK293
Accession #:
XP_005588053.1
Applications:
Bioactivity
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, ELISA(Det)
