7 results for "Kappa Opioid Receptor Agonists Small Molecules and Peptides" in Products
Kappa Opioid Receptor Agonists: Small Molecules and Peptides
The κ opioid receptor, (also known as OP2, KOP, KOR), is a member of the opioid family of G-protein-coupled receptors that also includes μ, δ and NOP receptors. Three variants of the receptor (designated κ1, κ2, and κ3) have been characterized. However only one cDNA clone has been identified, hence these receptor subtypes are likely to arise from interaction of one κ-opioid receptor protein with other membrane associated proteins.
κ Opioid receptors are ...
Selective κ agonist; more active enantiomer of (±)-U-50488 (Cat. No. 0495)
| Chemical Name: | trans-(-)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride |
| Purity: | ≥99% (HPLC) |
Potent and selective κ opioid receptor agonist; devoid of β-Arrestin-2 recruitment. Also induces differentiation of OPC.
| Alternate Names: | HY-163277,CS-0998107 |
| Chemical Name: | 3-(2-((1-Benzylazetidin-3-yl)(cyclobutylmethyl)amino)ethyl)phenol dihydrochloride |
| Purity: | ≥98% (HPLC) |
Selective κ agonist
| Chemical Name: | trans-(±)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride |
| Purity: | ≥99% (HPLC) |
Endogenous κ agonist
| Purity: | ≥95% (HPLC) |
Selective κ agonist; less active enantiomer of (±)-U-50488 (Cat. No. 0495)
| Chemical Name: | trans-(+)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]benzeneacetamide hydrochloride |
| Purity: | ≥99% (HPLC) |
κ agonist, acts peripherally
| Chemical Name: | (RS)-[3-[1-[[(3,4-Dichlorophenyl)acetyl]methylamino]-2-(1-pyrrolidinyl)ethyl]phenoxy]acetic acid hydrochloride |
| Purity: | ≥98% (HPLC) |
Subtype-selective κ agonist
| Chemical Name: | 4-[(3,4-Dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylic acid methyl ester fumarate |
| Purity: | ≥99% (HPLC) |
