(+)-U-50488 hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 0471
Selective κ agonist; less active enantiomer of (±)-U-50488 (Cat. No. 0495)
Key Product Details
Description
Selective κ agonist; less active enantiomer of (±)-U-50488 (Cat. No. 0495)
Product Description
(+)-U-50488 hydrochloride is a less active enantiomer of (±)-U-50488.Racemate and (-)-enantiomer also available.
Product Specifications
Molecular Weight
405.79
Formula
C19H26Cl2N2O.HCl
Storage
Store at RT
Purity
≥99% (HPLC)
Chemical Name
trans-(+)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]benzeneacetamide hydrochloride
CAS Number
114528-81-3
PubChem ID
6918162
InChI Key
KGMMGVIYOHGOKQ-JAXOOIEVSA-N
SMILES
O=C(CC3=CC(Cl)=C(Cl)C=C3)N([C@H]1[C@H](N2CCCC2)CCCC1)C.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 40.58 | 100 | |
| DMSO | 40.58 | 100 |
Preparing Stock Solutions
for (+)-U-50488 hydrochloride
The following data is based on the product molecular weight 405.79
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.46 mL | 12.32 mL | 24.64 mL |
| 5 mM | 0.49 mL | 2.46 mL | 4.93 mL |
| 10 mM | 0.25 mL | 1.23 mL | 2.46 mL |
| 50 mM | 0.05 mL | 0.25 mL | 0.49 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- De Costa Synthesis and absolute configuration of optically pure enantiomers of a κ-opioid receptor selective antagonist. FEBS Lett. 1987 PMID: 2822490
Product Specific Notices for (+)-U-50488 hydrochloride
For research use only
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