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JNK/c-jun Inhibitors Products

Members of the MAPK family, the c-Jun N-terminal kinases (JNKs) are activated by environmental stresses and inflammatory cytokines. Ten JNK isoforms are created by alternative splicing of mRNA transcripts derived from three genes: JNK1, JNK2, and JNK3. All JNKs are activated by dual phosphorylation; at T183/Y185 for JNK1 and 2, and T221/Y223 for JNK3. Activated JNKs translocate to the nucleus where they regulate the activity of several transcription factors; including the c-Jun component of AP-1 and ATF-2.

10 results for "JNK/c-jun Inhibitors" in Products

JNK/c-jun Inhibitors Products

Members of the MAPK family, the c-Jun N-terminal kinases (JNKs) are activated by environmental stresses and inflammatory cytokines. Ten JNK isoforms are created by alternative splicing of mRNA transcripts derived from three genes: JNK1, JNK2, and JNK3. All JNKs are activated by dual phosphorylation; at T183/Y185 for JNK1 and 2, and T221/Y223 for JNK3. Activated JNKs translocate to the nucleus where they regulate the activity of several transcription factors; including the c-Jun component of AP-1 and ATF-2.

10 results for "JNK/c-jun Inhibitors" in Products

Inhibitor of JNK signaling

High affinity JNK inhibitor; also inhibits HCMV replication

Peptide inhibitor of JNK/c-Jun interaction

Selective JNK inhibitor

Selective, competitive JNK inhibitor

Selective JNK inhibitor

Selective inhibitor of JNK2 and JNK3

Highly potent and selective JNK3 inhibitor

Inhibitor of JNK signaling

Selective JNK inhibitor

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