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IL-17/IL-17A: Proteins and Enzymes

IL-17/IL-17A is a homodimeric cytokine that is secreted by IL-23 activated Th17 and Tc17 cells. It is upregulated during inflammation and contributes to disease severity by enhancing neutrophil infiltration and the production of pro-inflammatory chemokines. IL-17A can additionally form bioactive heterodimers with IL-17F. IL-17A and the IL-17A/F heterodimer signal through widely expressed receptor complexes containing IL-17 RA and IL-17 RC.

8 results for "IL-17/IL-17A Proteins and Enzymes" in Products

IL-17/IL-17A: Proteins and Enzymes

IL-17/IL-17A is a homodimeric cytokine that is secreted by IL-23 activated Th17 and Tc17 cells. It is upregulated during inflammation and contributes to disease severity by enhancing neutrophil infiltration and the production of pro-inflammatory chemokines. IL-17A can additionally form bioactive heterodimers with IL-17F. IL-17A and the IL-17A/F heterodimer signal through widely expressed receptor complexes containing IL-17 RA and IL-17 RC.

8 results for "IL-17/IL-17A Proteins and Enzymes" in Products

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New rh IL-17A Available! ~4 fold better activity; HEK293 expressed; Lower endotoxin specification!

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A New and Improved rm IL-17A is now available! It is CHO expressed and has a lower endotoxin specification!

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