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Recombinant Human IL-17A (Human Cell-expressed) Protein

R&D Systems, Inc. a Bio-Techne Brand

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Recombinant Human IL-17A (Human Cell-expressed) Protein Bioactivity
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7955-IL-025

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7955-IL-010/CF
7955-IL-100/CF
7955-IL-025/CF
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Key Product Details

Source: HEK293
Accession #: Q16552
Structure / Form: Disulfide-linked homodimer
Applications: Bioactivity

Citations for Recombinant Human IL-17A (Human Cell-expressed) Protein (14)

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Customer Reviews for Recombinant Human IL-17A (Human Cell-expressed) Protein (3)

4.3 out of 5
3 customer ratings
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  • Recombinant Human IL-17A (Human Cell-expressed) Protein
    Name: Anonymous
    Application: In vitro bioactivity in cell culture
    Verified Customer | Posted 02/24/2021
  • Recombinant Human IL-17A (Human Cell-expressed) Protein
    Name: Rachel Levantovsky
    Application: In vitro bioactivity in cell culture
    Verified Customer | Posted 11/18/2020
  • Name: Anonymous
    Application: CellProlif
    Verified Customer | Posted 06/04/2019

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FAQs for Recombinant Human IL-17A (Human Cell-expressed) Protein

  • The specifications section on the website for Recombinant Human IL-17/IL-17A, Catalog # 7955-IL, describes SDS-PAGE as a range of Molecular Weights. Why? 

    Recombinant Human IL-17/IL-17A, Catalog # 7955-IL, has one N-linked glycosylation site  and seven O-linked glycosylation sites. The variable glycosylation results in multiple bands for this protein.

  • What are the diferences between Recombinant Human IL-17A Protein, CF (Catalog # 317-ILB) and Recombinant Human IL-17A (Human Cell-expressed) Protein (Catalog # 7955-IL)?

    There are multiple differences between Catalog # 317-ILB and 7955-IL.

    • 317-ILB is raised in E. coli, while 7955-IL is raised in Human Embryonic Kidney (HEK293) cells.
    • Human Cell-expressed 7955-IL has a lower endotoxin specification (<0.01 EU per 1 μg of the protein by the LAL method) compared to E. coli-expressed 317-ILB (<0.10 EU per 1 μg of the protein).
    • Human Cell-expressed 7955-IL exhibits greater activity in the CXCL1/GRO alpha secretion assay in HT‑29 human colon adenocarcinoma cells (0.12 - 1.2 ng/mL) compared to E. coli-expressed 317-ILB (0.4-4.0 ng/mL).

Product Documents for Recombinant Human IL-17A (Human Cell-expressed) Protein

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