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IL-12 Products

IL-12 (Interleukin-12) is a heterodimeric cytokine that consists of a p35 and a p40 subunit. p40 is also a subunit of the cytokine IL-23. IL-12 enhances the cytotoxic activity and induces IFN-gamma production in NK cells, T cells, and dendritic epidermal T cells, and it promotes a Th1 biased immune response. It signals through a receptor complex composed of IL-12 R beta 1 and IL-12 R beta 2. Both homodimeric p40, and IL-23 can bind to the IL-12 receptor, serving as non-signaling antagonists.

61 results for "IL-12" in Products

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IL-12 Products

IL-12 (Interleukin-12) is a heterodimeric cytokine that consists of a p35 and a p40 subunit. p40 is also a subunit of the cytokine IL-23. IL-12 enhances the cytotoxic activity and induces IFN-gamma production in NK cells, T cells, and dendritic epidermal T cells, and it promotes a Th1 biased immune response. It signals through a receptor complex composed of IL-12 R beta 1 and IL-12 R beta 2. Both homodimeric p40, and IL-23 can bind to the IL-12 receptor, serving as non-signaling antagonists.

61 results for "IL-12" in Products

HEK293-expressed Version Available!

BA

GS Linker, Defined heterodimer stoichiometry.

WB, CyTOF-ready, ICFlow
ICC, ICFlow

Recombinant Monoclonal Antibody.

WB, ICC, Neut
WB, CyTOF-ready, ICFlow
ICFlow
Catalog #: IC15701T
ICFlow

Recombinant Monoclonal Antibody.

Catalog #: MAB1570R
WB

Recombinant Monoclonal Antibody.

Catalog #: IC1570R
ICFlow
Catalog #: IC1570N
ICFlow
Catalog #: IC15701R
ICFlow

Recombinant Monoclonal Antibody.

Catalog #: IC15701V
ICFlow

Recombinant Monoclonal Antibody.

Catalog #: IC1171G
ICFlow
Catalog #: IC1171U
ICFlow
Catalog #: IC1570G
ICFlow
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