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IL-12 Products
IL-12 (Interleukin-12) is a heterodimeric cytokine that consists of a p35 and a p40 subunit. p40 is also a subunit of the cytokine IL-23. IL-12 enhances the cytotoxic activity and induces IFN-gamma production in NK cells, T cells, and dendritic epidermal T cells, and it promotes a Th1 biased immune response. It signals through a receptor complex composed of IL-12 R beta 1 and IL-12 R beta 2. Both homodimeric p40, and IL-23 can bind to the IL-12 receptor, serving as non-signaling antagonists.
60 results for "IL-12" in Products
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IL-12 Products
IL-12 (Interleukin-12) is a heterodimeric cytokine that consists of a p35 and a p40 subunit. p40 is also a subunit of the cytokine IL-23. IL-12 enhances the cytotoxic activity and induces IFN-gamma production in NK cells, T cells, and dendritic epidermal T cells, and it promotes a Th1 biased immune response. It signals through a receptor complex composed of IL-12 R beta 1 and IL-12 R beta 2. Both homodimeric p40, and IL-23 can bind to the IL-12 receptor, serving as non-signaling antagonists.
60 results for "IL-12" in Products
GS Linker, Defined heterodimer stoichiometry.
| Source : | HEK293 |
| Accession # : | P29460.1 (IL-12p40), P29459.2 (IL-12p35) |
| Applications : | Bioactivity |
Analyzed by SEC-MALS
| Source : | Sf 21 (baculovirus) |
| Accession # : | P29460 (p40) & P29459 (p35) |
| Applications : | Bioactivity |
| Source : | Sf 21 (baculovirus) |
| Accession # : | P43432 (p40) & NP_032377 (p35) |
| Applications : | Bioactivity |
| Assay Range : | 31.2 - 2,000 pg/mL |
| Applications : | ELISA |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
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| Sensitivity : | 2.5 pg/mL |
| Assay Range : | 7.8 - 500 pg/mL (Cell Culture Supernates, Serum) |
| Applications : | ELISA |
| Assay Range : | 39.1 - 2,500 pg/mL |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #24910 |
| Applications : | Block/Neutralize, Immunohistochemistry, Western Blot |
| Source : | HEK293 |
| Accession # : | P29459.2 |
| Applications : | Bioactivity |
| Source : | Sf 21 (baculovirus) |
| Accession # : | O02744 (p40) & O02743 (p35) |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #27537 |
| Applications : | Flow Cytometry |
GS Linker, Defined heterodimer stoichiometry.
| Source : | NS0 |
| Accession # : | P43432, P43431 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #24945 |
| Applications : | ELISA Capture, Immunocytochemistry/Immunofluorescence |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
GS Linker, Defined heterodimer stoichiometry.
| Source : | HEK293 |
| Accession # : | NP_001274204 (IL-12p40) & XP_005546300 (IL-12p35) |
| Applications : | Bioactivity |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Immunocytochemistry/Immunofluorescence, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG1 Clone #48110 |
| Applications : | ELISA Capture, Western Blot |
| Source : | CHO |
| Accession # : | P48095 (p40) & NP_001038199 (p35) |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #27537 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #116219 |
| Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Immunocytochemistry/Immunofluorescence, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Western Blot |
