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HMG-CoA Reductase Inhibitors: Small Molecules and Peptides

A transmembrane enzyme, 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMG-CoA reductase) catalyzes the rate limiting step in cholesterol biosynthesis - conversion of 3-hydroxy-3-methyl-glutaryl-CoA to mevalonic acid. It is bound to endoplasmic reticulum.

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6 results for "HMG-CoA Reductase Inhibitors Small Molecules and Peptides" in Products

6 results for "HMG-CoA Reductase Inhibitors Small Molecules and Peptides" in Products

HMG-CoA Reductase Inhibitors: Small Molecules and Peptides

A transmembrane enzyme, 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMG-CoA reductase) catalyzes the rate limiting step in cholesterol biosynthesis - conversion of 3-hydroxy-3-methyl-glutaryl-CoA to mevalonic acid. It is bound to endoplasmic reticulum.

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HMG-CoA reductase inhibitor

Chemical Name: (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyly-2,2-dimethyl butanoate
Purity: ≥98% (HPLC)
HMG-CoA reductase inhibitor

Potent HMG-CoA reductase inhibitor

Chemical Name: (±)-(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methyethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt
Purity: ≥98% (HPLC)
Potent HMG-CoA reductase inhibitor

Potent HMG-CoA reductase inhibitor

Chemical Name: (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl])-3,5-dihydroxyhept-6-enoic acid hemicalcium salt
Purity: ≥98% (HPLC)
Potent HMG-CoA reductase inhibitor

Potent HMG-CoA reductase inhibitor

Alternate Names: Mevinolin
Chemical Name: (2S)-(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl-2-methyl butanoate
Purity: ≥97% (HPLC)
Potent HMG-CoA reductase inhibitor

HMG-CoA reductase inhibitor

Alternate Names: Eptastatin sodium
Chemical Name: RR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid monosodium salt
Purity: ≥98% (HPLC)
HMG-CoA reductase inhibitor

HMG-CoA reductase inhibitor

Alternate Names: NK-104
Chemical Name: (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid hemicalcium salt
Purity: ≥98% (HPLC)
HMG-CoA reductase inhibitor
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