Histone Deacetylase 4/HDAC4: Small Molecules and Peptides
Histone Deacetylase (HDAC) family includes 18 enzymes. They are classified into two groups: the histone deacetylase family and the sirtuin family. The histone deacetylase family is divided into classes I, II and IV.
Products:
10 results for "Histone Deacetylase 4/HDAC4 Small Molecules and Peptides" in Products
10 results for "Histone Deacetylase 4/HDAC4 Small Molecules and Peptides" in Products
Histone Deacetylase 4/HDAC4: Small Molecules and Peptides
Histone Deacetylase (HDAC) family includes 18 enzymes. They are classified into two groups: the histone deacetylase family and the sirtuin family. The histone deacetylase family is divided into classes I, II and IV.
Products:
Histone deacetylase inhibitor
| Alternate Names: | 4-PB,Sodium phenylbutyrate |
| Chemical Name: | 4-Phenylbutyric acid, sodium salt |
| Purity: | ≥98% (HPLC) |
Histone deacetylase inhibitor
| Alternate Names: | VPA,Sodium Valproate |
| Chemical Name: | Sodium 2-propylpentanoate |
Potent and selective HDAC4 Degrader (PROTAC®)
| Chemical Name: | (2S,4R)-1-((3R,26S)-26-(tert-Butyl)-3-methyl-1,24-dioxo-5-propyl-1-(4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenyl)-10,13,16,19,22-pentaoxa-2,5,25-triazaheptacosan-27-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity: | ≥98% (HPLC) |
Potent histone deacetylase inhibitor
| Chemical Name: | (2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide |
| Purity: | ≥95% (HPLC) |
Pan-histone deacetylase inhibitor
| Chemical Name: | (2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide |
| Purity: | ≥98% (HPLC) |
Potent and selective class I histone deacetylase inhibitor; antitumor
| Alternate Names: | Depsipeptide,FR 901228,Romidepsin |
| Chemical Name: | Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl], cyclic (3-5) disulfide |
| Purity: | ≥98% (HPLC) |
Class I and II HDAC inhibitor
| Alternate Names: | Vorinostat |
| Chemical Name: | N-Hydroxy-N'-phenyloctanediamide |
| Purity: | ≥98% (HPLC) |
High affinity HDAC4 negative allosteric modulator; also binds S100A9; antiangiogenic
| Chemical Name: | 1,2-dihydro-4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-(trifluoromethyl)phenyl]-3-quinolinecarboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective class IIa HDAC inhibitor; brain penetrant
| Chemical Name: | 2-(2-Fluorophenyl)-N-hydroxy-2-(4-(5-(trifluoromethyl)pyrimidin-2-yl)phenyl)acetamide |
| Purity: | ≥98% (HPLC) |
Potent and selective HDAC class IIa inhibitor
| Chemical Name: | N-((R)-1-((S)-2-Methylpyrrolidin-1-yl)propan-2-yl)-4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide |
| Purity: | ≥98% (HPLC) |
