6 results for "Guanylyl Cyclase Activators" in Products
Guanylyl Cyclase Activators Products
Guanylyl Cyclases (GC) are a group of enzymes that, in the presence of a metal ion co-factor such as Mg2+ or Mn2+, convert guanosine-5'-triphosphate (GTP) into 3',5'-guanosine monophosphate (cGMP) and pyrophosphate. The second messenger cGMP participates in signaling by stimulating protein kinase G enzymes, altering the conductance of cGMP-gated ion channels and changing the activity of cGMP-regulated phosphodiesterases.
There are two main groups of guanylyl cyclase; soluble GC ...
Soluble guanylyl cyclase (sGC) activator; induces G1 cell cycle arrest
| Chemical Name: | 3-(5'-Hydroxymethyl-2'-furyl)-1-benzyl indazole |
| Purity: | ≥98% (HPLC) |
Endogenous activator of intestinal guanylyl cyclase
| Purity: | ≥95% (HPLC) |
Soluble guanylyl cyclase (sGC) activator
| Chemical Name: | 5-Cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine |
| Purity: | ≥98% (HPLC) |
Guanylyl cyclase (sGC) stimulator
| Chemical Name: | 2-[1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-morpholinyl)-4,6-pyrimidinediamine |
| Purity: | ≥98% (HPLC) |
Potent soluble guanylyl cyclase (sGC) activator
| Alternate Names: | Cinaciguat hydrochloride |
| Chemical Name: | 4-[[(4-Carboxybutyl)[2-[2-[[4-(2-phenylethyl)phenyl]methoxy]phenyl]ethyl]amino]methyl]benzoic acid hydrochloride |
| Purity: | ≥98% (HPLC) |
Water-soluble NO donor
| Alternate Names: | 3-Morpholinylsydnoneimine chloride |
| Chemical Name: | Amino-3-morpholinyl-1,2,3-oxadiazolium chloride |
| Purity: | ≥98% (HPLC) |
