Guanylin (human)
Tocris Bioscience, part of Bio-Techne | Catalog # 1898
Endogenous activator of intestinal guanylyl cyclase
Key Product Details
Description
Endogenous activator of intestinal guanylyl cyclase
Product Description
Guanylin (human) is an endogenous peptide activator of intestinal guanylyl cyclase; secreted mainly by the gastrointestinal mucosa. Regulates water and electrolyte transport in intestinal and renal epithelia.Product Specifications
Molecular Weight
1458.65
Formula
C58H87N15O21S4
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
183200-12-6
PubChem ID
90488722
InChI Key
XPNQMTAYRNMRRD-RDJGHUJSSA-N
SMILES
[H]N1CCC[C@H]1C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@H]1CSSC[C@@H]2NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H](C)NC(=O)[C@H](CSSC[C@H](NC(=O)CNC(=O)[C@@H](NC2=O)[C@@H](C)O)C(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC1=O)[C@@H](C)CC
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
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Background References
References are publications that support the biological activity of the product.
- Currie Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc.Natl.Acad.Sci.U.S.A. 1992 PMID: 1346555
- Nokihara Synthesis, solution structure, binding activity, and cGMP activation of human guanylin and its disulfide isomer. Regul.Pept. 1997 PMID: 9272623
- Beltowski Guanylin and related peptides. J.Physiol.Pharmacol. 2001 PMID: 11596856
Product Specific Notices for Guanylin (human)
For research use only
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