4 results for "Group II mGluR Antagonists" in Products
Group II mGluR Antagonists Products
Metabotropic Glutamate (mGlu) group II receptors are members of the metabotropic class of glutamate receptors, which also includes mGlu group I and mGlu group III receptors. Group II receptors are divided into two subtypes, mGlu2 and mGlu3. mGlu group II receptors are coupled to Gi/o, which inhibits adenylyl cyclase, decreasing the formation of cAMP. These receptors are involved in presynaptic inhibition and do not appear to affect postsynaptic membrane potential by themselves. The human genes for mGlu2 and mGlu3 receptors have been localized to chromosomes 3 (p21.1) and 7 (7q21.1-q21.2) respectively.
Non-selective mGlu antagonist; disodium salt of (RS)-MCPG (Cat. No. 0336)
| Chemical Name: | (RS)-α-Methyl-4-carboxyphenylglycine disodium salt |
| Purity: | ≥98% (HPLC) |
Selective, non-competitive mGlu2 antagonist
| Chemical Name: | (Z)-1-[2-Cycloheptyloxy-2-(2,6-dichlorophenyl)ethenyl]-1H-1,2,4-triazole |
| Purity: | ≥98% (HPLC) |
Non-selective mGlu antagonist; active isomer of (RS)-MCPG (Cat. No. 0336)
| Chemical Name: | (S)-α-Methyl-4-carboxyphenylglycine |
| Purity: | ≥98% (HPLC) |
Non-selective mGlu antagonist
| Chemical Name: | (RS)-α-Methyl-4-carboxyphenylglycine |
| Purity: | ≥98% (HPLC) |
