GABA-A R rho 1: Small Molecules and Peptides
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. GABA-A R rho 1 is a member of the rho subunit family and is highly expressed in the retina and in a lesser extent in brain, lung and thymus. GABA-A R rho 1 could play a role in retinal neurotransmission.
11 results for "GABA-A R rho 1 Small Molecules and Peptides" in Products
11 results for "GABA-A R rho 1 Small Molecules and Peptides" in Products
GABA-A R rho 1: Small Molecules and Peptides
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. GABA-A R rho 1 is a member of the rho subunit family and is highly expressed in the retina and in a lesser extent in brain, lung and thymus. GABA-A R rho 1 could play a role in retinal neurotransmission.
Competitive and selective GABAA antagonist
| Alternate Names: | Gabazine |
| Chemical Name: | 6-Imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid hydrobromide |
| Purity: | ≥98% (HPLC) |
Endogenous agonist
| Chemical Name: | γ-Aminobutyric acid |
Selective GABAA-ρ antagonist
| Chemical Name: | (1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid |
| Purity: | ≥97% (HPLC) |
Active metabolite of oxcarbazepine (Cat. No. 3864)
| Alternate Names: | GP 47779 |
| Chemical Name: | 10,11-Dihydro-10-hydroxy-5H-dibenz(Z)[b,f]azepin-5-carboxamide |
| Purity: | ≥98% (HPLC) |
GABAA agonist
| Alternate Names: | Gaboxadol |
| Chemical Name: | 4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3-ol hydrochloride |
| Purity: | ≥98% (HPLC) |
Postitive allosteric modulator of GABAA receptors
| Chemical Name: | (3α,5β)-3-Hydroxy-pregnan-20-one |
Positive allosteric modulator of GABAA receptors
| Alternate Names: | 3a,5a-THPROG |
| Chemical Name: | (3α,5α)-3-Hydroxy-pregnan-20-one |
Benzodiazepine antagonist
| Alternate Names: | Ro 15-1788 |
| Chemical Name: | 8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, ethyl ester |
| Purity: | ≥99% (HPLC) |
α5-selective GABAA inverse agonist
| Chemical Name: | 3-(1,1-Dimethylethyl)-7-(5-methyl-3-isoxazolyl)-2-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-pyrazolo[1,5-d][1,2,4]triazine |
| Purity: | ≥98% (HPLC) |
GABAA partial agonist; displays subtype selectivity
| Chemical Name: | 3-(2,5-Difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine |
| Purity: | ≥98% (HPLC) |
Benzodiazepine inverse agonist
| Chemical Name: | N-Methyl-β-carboline-3-carboxamide |
| Purity: | ≥99% (HPLC) |
