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Flumazenil

Tocris Bioscience a Bio-Techne Brand

Flumazenil | CAS No. 78755-81-4 | Benzodiazepine antagonist
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Key Product Details

Description: Benzodiazepine antagonist
Alternative Names: Ro 15-1788
Chemical Name: 8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, ethyl ester
Purity: ≥99% (HPLC)
Molecular Weight: 303.29

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Citations for Flumazenil (7)

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Customer Reviews for Flumazenil (2)

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  • Antagonism of Flumazenil to effects of Phenazepam
    Name: Anonymous
    Species: Other
    Assay Type: In Vitro
    Flumazenil (FMZ) was used to block action of other benzodiazepine ligand of GABA-A receptor (Phenazepam, PNZ) on decay kinetics of spontaneous inhibitory currents recorded from brain neurons of Prussian carp (Carassius gibelio). FMZ demonstrated competitive antagonism to PNZ in this research, both in vivo (behavioral tests) and in vitro (whole-cell voltage-clamp recordings, see example illustration).
    Soluble in DMSO, but requires sonication.
    Flumazenil Serum 1328
  • Flumazenil and in vivo chloride signals
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vivo
    used with fiber photometry to validate a chloride sensor in vivo. response to footshock was measured at baseline and then at 15 min intervals post injection
    injected 15mg/kg i.p at a concentration of.8mg/ml in 5% DMSO in saline
    Flumazenil Serum 1328

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Product Documents for Flumazenil

Certificate of Analysis

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