Key Product Details
Description: | GABAA agonist |
Alternative Names: | Gaboxadol |
Chemical Name: | 4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3-ol hydrochloride |
Purity: | ≥98% (HPLC) |
Molecular Weight: | 176.6 |
Customers also Viewed
Customers also Purchased
Citations for THIP hydrochloride (13)
Citations are publications that use Bio-Techne products. Selected citations for THIP hydrochloride include:
-
Green and Thayer et al.
(2019)
HIV gp120 upregulates tonic inhibition through α5-containing GABAARs.
Neuropharmacology.
149:161
PMID: 30797029 -
Ki and Lim
(2019)
Sleep-promoting effects of threonine link amino acid metabolism in Drosophila neuron to GABAergic control of sleep drive.
Elife.
8
PMID: 31313987 -
Montandon
(2017)
δ-subunit containing GABAA receptors modulate respiratory networks.
Sci Rep.
7(1):18105
PMID: 29273726 -
Patel et al.
(2016)
Context-Dependent Modulation of GABAAR-Mediated Tonic Currents.
J Neurophysiol.
36:607
PMID: 26758848 -
Tong et al.
(2015)
Ectopic Expression of α6 and δ GABAA Receptor Subunits in Hilar Somatostatin Neurons Increases Tonic Inhibition and Alters Network Activity in the Dentate Gyrus.
J Neurosci.
35:16142
PMID: 26658866 -
Seifi et al.
(2014)
Molecular and functional diversity of GABA-A receptors in the enteric nervous system of the mouse colon.
Nature.
34:10361
PMID: 25080596 -
Szemes et al.
(2013)
Weaker control of the electrical properties of cerebellar granule cells by tonically active GABAA receptors in the Ts65Dn mouse model of Down's syndrome.
Mol Brain.
6:33
PMID: 23870245 -
Asiedu et al.
(2012)
Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice.
J Pain.
13:546
PMID: 22537560 -
Ramaker et al.
(2012)
Effect of ganaxolone and THIP on operant and limited-access ethanol self-administration.
Neuropharmacology.
63:555
PMID: 22613838 -
Yue et al.
(2011)
Potentiating action of PropF. at GABAA receptors of retinal bipolar cells.
Invest Ophthalmol Vis Sci.
52:2497
PMID: 21071744 -
Schmid et al.
(2010)
Blindsight depends on the lateral geniculate nucleus.
PLoS One.
466:373
PMID: 20574422 -
Krook-Magnuson et al.
(2008)
Tonically active inhibition selectively controls feedforward circuits in mouse barrel cortex.
J Neurosci.
100:932
PMID: 18509076 -
Glykys
(2006)
Hippocampal network hyperactivity after selective reduction of tonic inhibition in GABA A receptor alpha5 subunit-deficient mice.
J Neurophysiol.
95:2796
PMID: 16452257
There are no citations that match your criteria.
Customer Reviews for THIP hydrochloride (1)
Customer Images
-
Species: MouseAssay Type: In VivoCell Line/Tissue: c57Bl6Jused with fiber photometry to validate chloride sensor in vivo. response to footshock was measured at baseline and at 20 min intervals post-injectioninjected 8mg/kg I.p. at 1mg/ml in saline
There are no reviews that match your criteria.