9 results for "Ferroptosis Inhibitors" in Products
Ferroptosis Inhibitors Products
Ferroptosis is a form of regulated cell death, distinct from apoptosis, necroptosis and autophagy. It is an iron-dependent process that results from the loss of glutathione peroxidase 4 (GPX4) activity, leading to accumulation of lipid peroxidation products and reactive oxygen species (ROS).
GPX4 is a selenoprotein that reduces hydrogen peroxide and lipid peroxides, while converting reduced glutathione (GSH) to its oxidized form; oxidized glutathione (glutathione disulfide) is recycled by ...
Potent ferroptosis inhibitor
| Chemical Name: | N-[(3-Chlorophenyl)methyl]spiro[piperidine-4,2'(1'H)-quinoxalin]-3'-amine hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective inhibitor of erastin induced ferroptosis
| Chemical Name: | Ethyl 3-amino-4-(cyclohexylamino)benzoate |
| Purity: | ≥98% (HPLC) |
Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT
| Chemical Name: | 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide |
| Purity: | ≥98% (HPLC) |
Ferroptosis suppressor protein 1 (FSP1) inhibitor; ferroptosis inducer
| Chemical Name: | 1-Amino-3-(4-methylphenyl)-pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile |
| Purity: | ≥98% (HPLC) |
Selective 15-lipoxygenase inhibitor
| Chemical Name: | 6,11-Dihydro[1]benzothiopyrano[4,3-b]indole |
| Purity: | ≥98% (HPLC) |
5-LOX inhibitor; orally bioavailable
| Alternate Names: | ICI D2138 |
| Chemical Name: | N-(1-Benzo[b]thien-2-ylethyl)-N-hydroxyurea |
| Purity: | ≥98% (HPLC) |
Antifade reagent; antioxidant vitamin E derivative; cell permeable and water soluble
| Chemical Name: | 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid |
| Purity: | ≥98% (HPLC) |
Induces ferroptosis; inhibits FSP1
| Chemical Name: | 3-(4-Bromophenyl)-6-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)thiazolo[2,3-c][1,2,4]triazole |
| Purity: | ≥98% (HPLC) |
Glutathione peroxidase mimic; peroxynitrite scavenger
| Chemical Name: | 2-Phenyl-1,2-benzisoselenazol-3(2H)-one |
| Purity: | ≥98% (HPLC) |
