3 results for "EAAT1/GLAST-1 Small Molecules and Peptides" in Products
EAAT1/GLAST-1: Small Molecules and Peptides
Excitatory Amino Acid Transporter 1 (EAAT1), also known as GLAST-1 and SLC1A3, is a member of the SDF symporter family of proteins. Human EAAT1/GLAST-1 is a 542 amino acid (aa), 8-transmembrane variably glycosylated protein with a predicted molecular weight of 60-62 kDa. Its N- and C-terminus are cytoplasmic. EAAT1/GLAST-1 homodimers are reported to exist, but only when the protein is glycosylated. There are at least two potential isoform variants. One shows an Arg substitution for aa 430-475, ...
Selective non-transportable inhibitor of EAATs
| Chemical Name: | DL-threo-β-Benzyloxyaspartic acid |
| Purity: | ≥98% (HPLC) |
GABA uptake inhibitor; also inhibits glutamate release and blocks NaV channels
| Chemical Name: | 2-Amino-6-trifluoromethoxybenzothiazole hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent competitive inhibitor of L-glutamate uptake
| Chemical Name: | 7-Chloro-4-hydroxyquinoline-2-carboxylic acid |
| Purity: | ≥98% (HPLC) |
