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E-Cadherin Products

E-Cadherin/Cadherin-1 (ECAD) Is a transmembrane cell adhesion protein. It forms homophilic clusters between epithelial cells and is a critical component of adherens junctions. These junctions are critical for the maintenance of the epithelial barrier and epithelial tissue homeostasis. Decreased E-Cadherin is associated with physiological and pathological epithelial-to-mesenchymal transition (EMT) and cell migration, and E-Cadherin loss contributes to cancer metastasis. The shed ECD is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation.

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788 results for "E-Cadherin" in Products

788 results for "E-Cadherin" in Products

E-Cadherin Products

E-Cadherin/Cadherin-1 (ECAD) Is a transmembrane cell adhesion protein. It forms homophilic clusters between epithelial cells and is a critical component of adherens junctions. These junctions are critical for the maintenance of the epithelial barrier and epithelial tissue homeostasis. Decreased E-Cadherin is associated with physiological and pathological epithelial-to-mesenchymal transition (EMT) and cell migration, and E-Cadherin loss contributes to cancer metastasis. The shed ECD is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation.

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Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies

Simple Plex Human E-Cadherin assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Recombinant Rabbit Monoclonal Antibody

Clone 67A4 was used by HLDA to establish CD designation.

Control for use with Human E-Cadherin Simple Plex Cartridge Kit

Contains 8 membranes - each spotted in duplicate with 15 different stem cell marker antibodies

Recombinant Monoclonal Antibody

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