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Cyr61/CCN1 Products
Cyr61, also known as IGFBP-10 and CCN1, is a 50 kDa matricellular glycoprotein that regulates the growth and adhesion of vascular endothelial cells, fibroblasts, and monocytes. Cyr61 induces VEGF upregulation, angiogenesis, and tumorigenesis through interactions with integrins alpha V beta 3, alpha V beta 5, alpha M beta 2, and alpha 6 beta 1. Cyr61 is cleaved by plasmin within its VWF domain which generates an N-terminal fragment that is not associated with the matrix but retains the ability to induce endothelial cell migration.
15 results for "Cyr61/CCN1" in Products
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Cyr61/CCN1 Products
Cyr61, also known as IGFBP-10 and CCN1, is a 50 kDa matricellular glycoprotein that regulates the growth and adhesion of vascular endothelial cells, fibroblasts, and monocytes. Cyr61 induces VEGF upregulation, angiogenesis, and tumorigenesis through interactions with integrins alpha V beta 3, alpha V beta 5, alpha M beta 2, and alpha 6 beta 1. Cyr61 is cleaved by plasmin within its VWF domain which generates an N-terminal fragment that is not associated with the matrix but retains the ability to induce endothelial cell migration.
15 results for "Cyr61/CCN1" in Products
| Sensitivity : | 3.8 pg/mL |
| Assay Range : | 39.1 - 2,500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Saliva, Human Milk) |
| Applications : | ELISA |
| Source : | CHO |
| Accession # : | O00622 |
| Applications : | Bioactivity |
Simple Plex Human Cyr61/CCN1 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Immunohistochemistry, Simple Western, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #365108 |
| Applications : | Western Blot |
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | ELISA, Simple Western, Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2b Clone #466305 |
| Applications : | Immunohistochemistry |
| Assay Range : | 31.2 - 2,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #434311 |
| Applications : | ELISA |
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies
