Chitinase 3-like 1/YKL-40 Products
Chitinase 3-like 1/YKL-40 (CHI3L1), also called BRP39 in mouse, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family although it does not show chitotriosidase activity. CHI3L1 is expressed by articular chondrocytes, synovial cells, activated monocyte-derived macrophages, neutrophils, endothelial cells, vascular smooth muscle cells, and some cancer cells.
CHI3L1 binds to chitin and heparins, and it enhances cell adhesion, proliferation and tumor angiogenesis. Circulating CHI3L1 is elevated during inflammation and connective tissue remodeling such as arthritis, chronic obstructive pulmonary disease, diabetes, cardiovascular disease, inflammatory bowel disease, and liver cirrhosis. It is frequently upregulated in glioblastoma, myxoid chondrosarcoma, melanoma, and carcinomas of the breast, thyroid, colon, lung, kidney, and ovary.
Products:
278 results for "Chitinase 3-like 1/YKL-40" in Products
278 results for "Chitinase 3-like 1/YKL-40" in Products
Chitinase 3-like 1/YKL-40 Products
Chitinase 3-like 1/YKL-40 (CHI3L1), also called BRP39 in mouse, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family although it does not show chitotriosidase activity. CHI3L1 is expressed by articular chondrocytes, synovial cells, activated monocyte-derived macrophages, neutrophils, endothelial cells, vascular smooth muscle cells, and some cancer cells.
CHI3L1 binds to chitin and heparins, and it enhances cell adhesion, proliferation and tumor angiogenesis. Circulating CHI3L1 is elevated during inflammation and connective tissue remodeling such as arthritis, chronic obstructive pulmonary disease, diabetes, cardiovascular disease, inflammatory bowel disease, and liver cirrhosis. It is frequently upregulated in glioblastoma, myxoid chondrosarcoma, melanoma, and carcinomas of the breast, thyroid, colon, lung, kidney, and ovary.
Products:
| Sensitivity: | 8.15 pg/mL |
| Applications: | ELISA |
| Assay Range: | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
| Applications: | Simple Plex |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC, ICC |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Applications: | Simple Plex |
| Source: | NS0 |
| Accession #: | P36222 |
| Applications: | BA |
| Reactivity: | Human, Primate |
| Details: | Rat IgG1 Monoclonal Clone #384327 |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #321924 |
| Applications: | WB |
| Sensitivity: | 16 pg/mL |
| Applications: | ELISA |
| Assay Range: | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Simple Western, IP |
| Reactivity: | Human, Primate |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Applications: | Ctrl, Simple Plex |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #CL12241 |
| Applications: | IHC |
![Chitinase 3-like 1/YKL-40 Antibody (CL12241) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp3-44298cl1_mouse-chitinase-3-like-1-ykl-40-mab-cl12241-corafluor-1-810202512485416.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Mouse |
| Details: | Rat IgG2B Monoclonal Clone #321924 |
| Applications: | IHC, WB |
| Reactivity: | Human, Primate |
| Details: | Rat IgG1 Monoclonal Clone #384327 |
| Applications: | Func, B/N, ELISA(Cap) |
![Chitinase 3-like 1/YKL-40 Antibody (384327) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/fab25991cl1_rat-mab-384327-corafluor-1-26920251749413.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #101 |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #CL12314 |
| Applications: | IHC |
![Chitinase 3-like 1/YKL-40 Antibody (CL12314) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp3-44361cl1_mouse-chitinase-3-like-1-ykl-40-mab-cl12314-corafluor-1-29102025125822.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #anti-CHI3L1 |
| Applications: | ELISA, Flow, Func |
| Source: | NS0 |
| Accession #: | Q61362 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Chitinase 3-like 1/YKL-40 Antibody [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/af2599cl1_goat-chitinase-3-like-1-ykl-40-pab-corafluor-1-8102025944105.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #CL12241 |
| Applications: | IHC, WB |
![Chitinase 3-like 1/YKL-40 Antibody (CL12241) - Azide and BSA Free Immunohistochemistry-Paraffin: Chitinase 3-like 1/YKL-40 Antibody [NBP3-44298]](https://resources.bio-techne.com/images/products/nbp3-44298_mouse-chitinase-3-like-1-ykl-40-mab-cl12241-azide-bsa-free-282202512163678.jpg "Immunohistochemistry-Paraffin: Chitinase 3-like 1/YKL-40 Antibody [NBP3-44298]")