CD47 Products
CD47, also known as Integrin-Associated Protein (IAP) and OA3, is a ubiquitous transmembrane protein that binds to SIRP family members on macrophages, neutrophils, and T cells. These interactions prevent macrophage-mediated clearance of healthy CD47-expressing cells and promote immune cell transmigration across the vascular endothelium. CD47 associates in cis with Fas on T cells and enhances Fas-mediated apoptosis; its ligation promotes T cell anergy and dampens Th1 immune responses. CD47 also associates in cis with several Integrins which can positively or negatively modulate Integrin-mediated function. CD47 binding by Thrombospondin-1 inhibits the angiogenic and vasorelaxant effects of nitric oxide. On dendritic cells and myeloma cells, CD47 ligation by TSP-1 induces giant cell formation and osteoclast differentiation.
631 results for "CD47" in Products
631 results for "CD47" in Products
CD47 Products
CD47, also known as Integrin-Associated Protein (IAP) and OA3, is a ubiquitous transmembrane protein that binds to SIRP family members on macrophages, neutrophils, and T cells. These interactions prevent macrophage-mediated clearance of healthy CD47-expressing cells and promote immune cell transmigration across the vascular endothelium. CD47 associates in cis with Fas on T cells and enhances Fas-mediated apoptosis; its ligation promotes T cell anergy and dampens Th1 immune responses. CD47 also associates in cis with several Integrins which can positively or negatively modulate Integrin-mediated function. CD47 binding by Thrombospondin-1 inhibits the angiogenic and vasorelaxant effects of nitric oxide. On dendritic cells and myeloma cells, CD47 ligation by TSP-1 induces giant cell formation and osteoclast differentiation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #CD47/3019 |
| Applications: | IHC, ELISA, ICC/IF, Flow, MA |
![Immunocytochemistry/ Immunofluorescence: CD47 Antibody (CD47/3019) [NBP3-08975]](https://resources.bio-techne.com/images/products/CD47-Antibody-CD47-3019-Immunocytochemistry-Immunofluorescence-NBP3-08975-img0004.jpg "Immunocytochemistry/ Immunofluorescence: CD47 Antibody (CD47/3019) [NBP3-08975]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #CD47/3019 |
| Applications: | IHC, ELISA, ICC/IF, Flow, MA |
![Immunocytochemistry/ Immunofluorescence: CD47 Antibody (CD47/3019) - Azide and BSA Free [NBP3-08976]](https://resources.bio-techne.com/images/products/CD47-Antibody-CD47-3019-Azide-and-BSA-Free-Immunocytochemistry-Immunofluorescence-NBP3-08976-img0002.jpg "Immunocytochemistry/ Immunofluorescence: CD47 Antibody (CD47/3019) - Azide and BSA Free [NBP3-08976]")
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CD47/6362R |
| Applications: | IHC, ELISA |
![Immunohistochemistry-Paraffin: CD47 Antibody (CD47/6362R) [NBP3-07224]](https://resources.bio-techne.com/images/products/CD47-Antibody-CD47-6362R-Immunohistochemistry-Paraffin-NBP3-07224-img0002.jpg "Immunohistochemistry-Paraffin: CD47 Antibody (CD47/6362R) [NBP3-07224]")
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CD47/6362R |
| Applications: | IHC, ELISA |
![Immunohistochemistry-Paraffin: CD47 Antibody (CD47/6362R) - Azide and BSA Free [NBP3-08218]](https://resources.bio-techne.com/images/products/CD47-Antibody-CD47-6362R-Azide-and-BSA-Free-Immunohistochemistry-Paraffin-NBP3-08218-img0001.jpg "Immunohistochemistry-Paraffin: CD47 Antibody (CD47/6362R) - Azide and BSA Free [NBP3-08218]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #CD47/3019 |
| Applications: | IHC, ELISA, ICC/IF, Flow, MA |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #CD47/3019 |
| Applications: | IHC, ELISA, ICC/IF, Flow, MA |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #CD47/3019 |
| Applications: | IHC, ELISA, ICC/IF, Flow, MA |
![CD47 Antibody (CD47/3019) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp3-08976cl1_mouse-cd47-mab-cd47-3019-corafluor-1-810202512305214.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CD47/6362R |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CD47/6362R |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CD47/6362R |
| Applications: | IHC, ELISA |
![CD47 Antibody (CD47/6362R) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp3-08218cl1_rabbit-cd47-mab-cd47-6362r-corafluor-1-29920251526217.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #CD47/3019 |
| Applications: | IHC, ELISA, ICC/IF, Flow, MA |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #CD47/3019 |
| Applications: | IHC, ELISA, ICC/IF, Flow, MA |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #CD47/3019 |
| Applications: | IHC, ELISA, ICC/IF, Flow, MA |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #CD47/3019 |
| Applications: | IHC, ELISA, ICC/IF, Flow, MA |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #CD47/3019 |
| Applications: | IHC, ELISA, ICC/IF, Flow, MA |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Flow, IHC, CyTOF-ready, KO, +1 More |
| Reactivity: | Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #B6H12.2 |
| Applications: | IHC, WB, ICC/IF, Flow, IP, +1 More |
![Immunocytochemistry/ Immunofluorescence: CD47 Antibody (B6H12.2) - Azide and BSA Free [NBP2-31106]](https://resources.bio-techne.com/images/products/CD47-Antibody-B6H12-2-Azide-Free-Immunocytochemistry-Immunofluorescence-NBP2-31106-img0012.jpg "Immunocytochemistry/ Immunofluorescence: CD47 Antibody (B6H12.2) - Azide and BSA Free [NBP2-31106]")
| Reactivity: | Human |
| Details: | Rabbit Monoclonal Clone #BLR131H |
| Applications: | IHC, WB, ICC/IF, Simple Western |
![Western Blot: CD47 Antibody (BLR131H) [NBP3-14713]](https://resources.bio-techne.com/images/products/CD47-Antibody-BLR131H-Western-Blot-NBP3-14713-img0001.jpg "Western Blot: CD47 Antibody (BLR131H) [NBP3-14713]")
| Source: | NS0 |
| Accession #: | Q08722 |
| Applications: | BA, BA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR1983 |
| Applications: | WB, ICC/IF, Flow |
| Source: | NS0 |
| Accession #: | NP_034711 |
| Applications: | BA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Kappa/IgG1 Kappa Monoclonal Clone #IAP/964 + B6H12.2 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready, +1 More |
![Immunocytochemistry/ Immunofluorescence: CD47 Antibody (IAP/964 + B6H12.2) - Azide and BSA Free [NBP2-47812]](https://resources.bio-techne.com/images/products/CD47-Antibody-IAP-964-+-B6H12-2-Azide-and-BSA-Free-Immunocytochemistry-Immunofluorescence-NBP2-47812-img0002.jpg "Immunocytochemistry/ Immunofluorescence: CD47 Antibody (IAP/964 + B6H12.2) - Azide and BSA Free [NBP2-47812]")
| Source: | NS0 |
| Accession #: | Q08722 |
| Applications: | BA |
