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10 results for "CCL4/MIP-1 beta" in Products

CCL4/MIP-1 beta Products

CCL4/MIP-1 beta is a beta chemokine that is secreted at sites of inflammation by activated leukocytes, lymphocytes, vascular endothelial cells, and pulmonary smooth muscle cells. It attracts a variety of immune cells to sites of microbial infection as well as to other pathologic inflammation such as allergic asthma and ischemic myocardium. CCL4 is secreted from activated monocytes as a heterodimer with CCL3/MIP-1 alpha. It signals through CCR5, and an N-terminally trimmed form additionally interacts with CCR1 and CCR2. In humans, the ability of CCL4 to bind CCR5 inhibits the cellular entry of M-tropic HIV-1 which utilizes CCR5 as a coreceptor.

Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, B/N, ICC/IF
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, B/N, ICC/IF
Reactivity:
Cotton Rat
Details:
Goat IgG Polyclonal
Applications:
WB, B/N
Reactivity:
Canine
Details:
Sheep IgG Polyclonal
Applications:
WB, ICC/IF
Reactivity:
Rat
Details:
Sheep IgG Polyclonal
Applications:
WB, B/N
Reactivity:
Cotton Rat
Details:
Mouse IgG1 Monoclonal Clone #163910
Applications:
WB, B/N
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #93342
Applications:
WB, Flow, CyTOF-ready
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #93321
Applications:
WB, B/N, ICC/IF
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #24006
Applications:
WB, ELISA(Cap), B/N, Flow, CyTOF-ready
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #46907
Applications:
B/N
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