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CCL21/6Ckine Products

CCL21, also known as 6Ckine, TCA-4, SLC, Exodus-2, and A21, is a homeostatic chemokine that signals through CCR7 or CXCR3. CCL21 is constitutively presented on initial lymphatic vessels, high endothelial venules (HEV), and lymph node dendritic cells (DC) where it promotes the docking of DC to lymphatic vessels and the retention of T cells by lymph node DC, resulting in T cell priming for activation. Its upregulation during chronic inflammation or tissue damage promotes fibrosis, inflammatory cytokine production, and neuropathic pain. The soluble chemokine is elevated in rheumatoid arthritis synovial fluid and in the serum of coronary artery disease patients.

111 results for "CCL21/6Ckine" in Products

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CCL21/6Ckine Products

CCL21, also known as 6Ckine, TCA-4, SLC, Exodus-2, and A21, is a homeostatic chemokine that signals through CCR7 or CXCR3. CCL21 is constitutively presented on initial lymphatic vessels, high endothelial venules (HEV), and lymph node dendritic cells (DC) where it promotes the docking of DC to lymphatic vessels and the retention of T cells by lymph node DC, resulting in T cell priming for activation. Its upregulation during chronic inflammation or tissue damage promotes fibrosis, inflammatory cytokine production, and neuropathic pain. The soluble chemokine is elevated in rheumatoid arthritis synovial fluid and in the serum of coronary artery disease patients.

111 results for "CCL21/6Ckine" in Products

WB, IHC, CyTOF-ready, ICFlow, Neut
WB, IHC, CyTOF-ready, ICFlow
WB, Simple Western, ICC, Neut
WB
WB
WB
BA, BA
WB
ICFlow
Catalog #: IC457S
ICFlow
WB

Recombinant Monoclonal Antibody.

ICFlow
Catalog #: IC457U
ICFlow
Catalog #: IC457T
ICFlow
Catalog #: IC457R
ICFlow
Catalog #: IC457N
ICFlow
BA
ICC/IF, IHC, WB
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