Caspase-2 Products
Caspase-2, also known as NEDD2 and ICH-1, is a 30‑32 kDa member of the peptidase C14A/IL‑1 beta‑converting family of enzymes. It is widely expressed and is an integral component of the apoptotic cascade. Caspase-2 is a disulfide-linked homodimer, with activation occurring following oligomerization within the context of activating platforms such as DISC (death-inducing signaling complex) or the PIDDosome.
Initially, Pro-Caspase-2 is cleaved into a p34 subunit and a p14 subunit which are further processed to generate the prodomain, plus the mature p18 and p12 subunits. Notably, each p18-p12 heterodimer demonstrates proteolytic activity and localizes to either the nucleus or cytoplasm.
136 results for "Caspase-2" in Products
136 results for "Caspase-2" in Products
Caspase-2 Products
Caspase-2, also known as NEDD2 and ICH-1, is a 30‑32 kDa member of the peptidase C14A/IL‑1 beta‑converting family of enzymes. It is widely expressed and is an integral component of the apoptotic cascade. Caspase-2 is a disulfide-linked homodimer, with activation occurring following oligomerization within the context of activating platforms such as DISC (death-inducing signaling complex) or the PIDDosome.
Initially, Pro-Caspase-2 is cleaved into a p34 subunit and a p14 subunit which are further processed to generate the prodomain, plus the mature p18 and p12 subunits. Notably, each p18-p12 heterodimer demonstrates proteolytic activity and localizes to either the nucleus or cytoplasm.
| Source: | E. coli |
| Accession #: | P42575 |
| Applications: | EnzAct |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey |
| Details: | Rat IgG2a Kappa Monoclonal Clone #10C6 |
| Applications: | IHC, ELISA, ICC/IF, Flow |
![Immunocytochemistry/ Immunofluorescence: Caspase-2 Antibody (10C6) - BSA Free [NBP2-80095]](https://resources.bio-techne.com/images/products/Caspase-2-Antibody-10C6-BSA-Free-Immunocytochemistry-Immunofluorescence-NBP2-80095-img0004.jpg "Immunocytochemistry/ Immunofluorescence: Caspase-2 Antibody (10C6) - BSA Free [NBP2-80095]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR1824 |
| Applications: | IHC, WB, ICC/IF, Flow |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey |
| Details: | Rat IgG2a Kappa Monoclonal Clone #11B4 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +1 More |
![Western Blot: Caspase-2 Antibody (11B4)BSA Free [NBP2-80096]](https://resources.bio-techne.com/images/products/Caspase-2-Antibody-11B4-BSA-Free-Western-Blot-NBP2-80096-img0001.jpg "Western Blot: Caspase-2 Antibody (11B4)BSA Free [NBP2-80096]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #691233 |
| Applications: | ICC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #691233 |
| Applications: | ICC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #691233 |
| Applications: | ICC |
| Reactivity: | Human |
| Details: | Mouse IgM Kappa Monoclonal Clone #18E809.3 |
| Applications: | WB |
![Western Blot: Caspase-2 Antibody (18E809.3) [NB100-56686]](https://resources.bio-techne.com/images/products/Caspase-2-Antibody-18E809-3-Western-Blot-NB100-56686-img0002.jpg "Western Blot: Caspase-2 Antibody (18E809.3) [NB100-56686]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #1C11 |
| Applications: | WB, ELISA, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Caspase-2 Antibody (1C11) - (active/cleaved) [H00000835-M10]](https://resources.bio-techne.com/images/products/Caspase-2-Antibody-1C11-active-cleaved-Immunocytochemistry-Immunofluorescence-H00000835-M10-img0001.jpg "Immunocytochemistry/ Immunofluorescence: Caspase-2 Antibody (1C11) - (active/cleaved) [H00000835-M10]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #691233 |
| Applications: | ICC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Caspase-2 Antibody [NBP2-38635]](https://resources.bio-techne.com/images/products/Caspase-2-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-38635-img0003.jpg "Immunocytochemistry/ Immunofluorescence: Caspase-2 Antibody [NBP2-38635]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #691233 |
| Applications: | ICC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #691233 |
| Applications: | ICC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #691233 |
| Applications: | ICC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #691233 |
| Applications: | ICC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #691233 |
| Applications: | ICC |
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #3D4 |
| Applications: | IHC, WB, ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #4-1-5 |
| Applications: | WB |
![Western Blot: Caspase-2 Antibody (4-1-5) [NBP1-19194]](https://resources.bio-techne.com/images/products/NBP1-19194.jpg "Western Blot: Caspase-2 Antibody (4-1-5) [NBP1-19194]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2Z10F1 |
| Applications: | WB |
![Western Blot: Caspase-2 Antibody (2Z10F1) [NBP3-16501]](https://resources.bio-techne.com/images/products/Caspase-2-Antibody-2Z10F1-Western-Blot-NBP3-16501-img0001.jpg "Western Blot: Caspase-2 Antibody (2Z10F1) [NBP3-16501]")
| Applications: | ELISA |
| Applications: | ELISA |
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #7E5 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey |
| Details: | Rat IgG2a Kappa Monoclonal Clone #10C6 |
| Applications: | IHC, ELISA, ICC/IF, Flow |
