Carbonic Anhydrase XII/CA12: Small Molecules and Peptides
Carbonic anhydrases catalyze the reversible reaction of CO2 + H2O = HCO3- + H+, which is fundamental to many processes such as respiration, renal tubular acidification and bone resorption. Human members of the CAs are secreted (CA6), membrane-bound (CA4, 9 to 12 and 14), cytosolic (CA1 to 3, 7, 8 and 13) or mitochondrial (CA5A and 5B). Some CAs may serve as markers for tumors and hypoxia. A subset of CAs lack CA activity due to point mutations but retain esterase function.
5 results for "Carbonic Anhydrase XII/CA12 Small Molecules and Peptides" in Products
5 results for "Carbonic Anhydrase XII/CA12 Small Molecules and Peptides" in Products
Carbonic Anhydrase XII/CA12: Small Molecules and Peptides
Carbonic anhydrases catalyze the reversible reaction of CO2 + H2O = HCO3- + H+, which is fundamental to many processes such as respiration, renal tubular acidification and bone resorption. Human members of the CAs are secreted (CA6), membrane-bound (CA4, 9 to 12 and 14), cytosolic (CA1 to 3, 7, 8 and 13) or mitochondrial (CA5A and 5B). Some CAs may serve as markers for tumors and hypoxia. A subset of CAs lack CA activity due to point mutations but retain esterase function.
Carbonic anhydrase inhibitor
| Chemical Name: | N-[5-(Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide |
| Purity: | ≥98% (HPLC) |
GluK1 antagonist; inhibits carbonic anhydrase (CA) II and IV; also positive allosteric modulator of GABAA receptors
| Alternate Names: | Topamax |
| Chemical Name: | 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate |
| Purity: | ≥98% (HPLC) |
High affinity and selective CA IX and CA XII inhibitor
| Chemical Name: | 4-[[[(3,5-Dimethylphenyl)amino]carbonyl]amino]phenyl sulfamate |
| Purity: | ≥98% (HPLC) |
Standard selective D2-like antagonist
| Chemical Name: | (RS)-(±)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide |
| Purity: | ≥98% (HPLC) |
Selective and potent COX-2 inhibitor
| Chemical Name: | 4-(5-Methyl-3-phenylisoxazol-4-yl)benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
