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Bax Products
B cell leukemia/lymphoma-2 associated X protein (Bax) is a pro-apoptotic member of the Bcl-2 family of proteins found in many cell types. Bax is a cytosolic protein that translocates to the mitochondria and participates in Cytochrome c release in response to apoptotic stimuli. Aberrant expression of Bcl-2 family members can inappropriately promote or prevent apoptosis. Increased expression of Bax is associated with the apoptotic loss of neurons in Parkinson's disease.
9 results for "Bax" in Products
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Bax Products
B cell leukemia/lymphoma-2 associated X protein (Bax) is a pro-apoptotic member of the Bcl-2 family of proteins found in many cell types. Bax is a cytosolic protein that translocates to the mitochondria and participates in Cytochrome c release in response to apoptotic stimuli. Aberrant expression of Bcl-2 family members can inappropriately promote or prevent apoptosis. Increased expression of Bax is associated with the apoptotic loss of neurons in Parkinson's disease.
9 results for "Bax" in Products
Contains 4 membranes - each spotted in duplicate with 35 different apoptosis antibodies
| Assay Range : | 312 - 20,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Knockout Validated, Simple Western, Western Blot |
High affinity and selective activator of Bax
| Chemical Name : | 2-[(2-Nitro-9H-fluorene-9-ylidene)methyl]phenol |
| Purity : | ≥98% (HPLC) |
Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines
| Chemical Name : | 4-[4-[(4'-Chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide |
| Purity : | ≥98% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #127606 |
| Applications : | Immunocytochemistry/Immunofluorescence, Knockout Validated, Western Blot |
Allosteric inhibitor of Bax channel activation
| Alternate Names : | BAI1 |
| Chemical Name : | 3,6-Dibromo-α-(1-piperazinylmethyl)-9H-carbazole-9-ethanol dihydrochloride |
| Purity : | ≥98% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #127602 |
| Applications : | Immunocytochemistry/Immunofluorescence, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Western Blot |
