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Akt3: Small Molecules and Peptides

Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.

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6 results for "Akt3 Small Molecules and Peptides" in Products

6 results for "Akt3 Small Molecules and Peptides" in Products

Akt3: Small Molecules and Peptides

Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.

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Potent and selective allosteric Akt1, Akt2 and Akt3 inhibitor

Chemical Name: 8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride
Purity: ≥98% (HPLC)
Potent and selective allosteric Akt1, Akt2 and Akt3 inhibitor

Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral

Alternate Names: Triciribine,NSC 154020,TCN
Chemical Name: 1,5-Dihydro-5-methyl-1-β-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine
Purity: ≥98% (HPLC)
Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral

Akt activator

Chemical Name: 2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester
Akt activator

Selective Akt/PKB inhibitor

Alternate Names: Akt Inhibitor X
Chemical Name: 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride
Purity: ≥98% (HPLC)
Selective Akt/PKB inhibitor

Potent pan-Akt and PKA inhibitor

Chemical Name: 4-(4-Chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine hydrochloride
Purity: ≥98% (HPLC)
Potent pan-Akt and PKA inhibitor

Akt kinase inhibitor. Antitumor

Chemical Name: 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol
Purity: ≥98% (HPLC)
Akt kinase inhibitor. Antitumor
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