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Aconitase 1 Products

Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.
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14 results for "Aconitase 1" in Products

Aconitase 1 Products

Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.
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14 results for "Aconitase 1" in Products

ELISA, IP, WB
ELISA, Flow, ICC/IF, WB

Recombinant monoclonal antibody expressed in HEK293F cells

ICC/IF, WB
Catalog #: NBP1-87677PEP
AC
ICC/IF, WB

Recombinant Monoclonal Antibody

IHC, WB
ELISA, WB
ELISA
PAGE
Catalog #: NBP1-87678PEP
AC
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