63 results for "5-HT7" in Products
5-HT7 Products
The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. This isoform (A) is the predominant isoform in spleen, caudate and hippocampus. 5-HT7 isoform B is expressed at lower levels. 5-HT7 belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Pharmacological and genetic tools targeting 5-HT7 in preclinical animal models have implicated this receptor in diverse (patho)physiological processes of the central nervous system (CNS).
![Western Blot: 5-HT7 Antibody [NB100-56352]](https://resources.rndsystems.com/images/products/5-HT7-Antibody-Western-Blot-NB100-56352-img0003.jpg "Western Blot: 5-HT7 Antibody [NB100-56352]")
![Immunohistochemistry-Paraffin: 5-HT7 Antibody [NBP1-46598]](https://resources.rndsystems.com/images/products/5-HT7-Antibody-Immunohistochemistry-Paraffin-NBP1-46598-img0002.jpg "Immunohistochemistry-Paraffin: 5-HT7 Antibody [NBP1-46598]")
5-HT1 agonist; also has high affinity for 5-ht5a and 5-HT7
Recombinant Monoclonal Antibody
![Western Blot: 5-HT7 Antibody (4E6D2) [NBP3-15870]](https://resources.rndsystems.com/images/products/5-HT7-Antibody-4E6D2-Western-Blot-NBP3-15870-img0003.jpg "Western Blot: 5-HT7 Antibody (4E6D2) [NBP3-15870]")
Potent and selective 5-HT7 antagonist; brain penetrant
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant
Endogenous 5-HT receptor agonist
Potent and selective 5-HT7 antagonist; brain penetrant
Potent 5-HT7 agonist
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant
![5-HT7 Antibody (1015322) [Allophycocyanin]](https://resources.rndsystems.com/images/products/fab10325a_mouse-monoclonal-5-ht7-antibody-1015322-allophycocyanin-flow-cytometry-54202412315..jpg "Detection of 5-HT7 in 5-HT7 HEK293/eGFP transfecants vs Irrelevant HEK293/eGFP transfecants by Flow Cytometry")
![Western Blot: 5-HT7 Antibody [NBP1-44051]](https://resources.rndsystems.com/images/products/5-HT7-Antibody-Western-Blot-NBP1-44051-img0003.jpg "Western Blot: 5-HT7 Antibody [NBP1-44051]")
![Immunohistochemistry-Paraffin: 5-HT7 Antibody [NBP3-14527]](https://resources.rndsystems.com/images/products/5-HT7-Antibody-Immunohistochemistry-Paraffin-NBP3-14527-img0001.jpg "Immunohistochemistry-Paraffin: 5-HT7 Antibody [NBP3-14527]")
Recombinant Monoclonal Antibody
![Immunohistochemistry: 5-HT7 Antibody [NBP2-68957]](https://resources.rndsystems.com/images/products/5-HT7-Antibody-Immunohistochemistry-NBP2-68957-img0001.jpg "Immunohistochemistry: 5-HT7 Antibody [NBP2-68957]")
![Western Blot: 5-HT7 Overexpression Lysate [NBP2-06701]](https://resources.rndsystems.com/images/products/5HT7-Receptor-Overexpression-Lysate-Native-Western-Blot-NBP2-06701-img0002.jpg "Western Blot: 5-HT7 Overexpression Lysate [NBP2-06701]")