5-HT7 HEK293/eGFP transfecants (A) vs Irrelevant HEK293/eGFP transfecants (B) were stained with Mouse Anti-Human 5-HT7 APC-conjugated Monoclonal Antibody (Catalog # FAB10325A). View our protocol for Staining Membrane-associated Proteins.

Applications for Human 5-HT7 APC-conjugated Antibody

Application

Recommended Usage

Flow Cytometry

10 µL/10⁶ cells
Sample: Transfectants (see below)

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Formulation

Supplied in a saline solution containing Tris, NaCl and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: 5-HT7

HTR2B is a G-protein coupled receptor for serotonin. The 5HT2 receptors mediate many of the central and peripheral physiologic functions of serotonin. 5HT2B plays a role in the regulation of dopamine and serotonin release, serotonin uptake and in the regulation of extracellular dopamine and serotonin levels. It also plays a role in pulmonary vasoconstriction and regulating cardiac structure and functions. 5HT2B receptors were shown to be expressed in human failing heart and have been strongly implicated in drug induced valvular heart disease.

Long Name

5-Hydroxytryptamine Receptor 7

Alternate Names

5-HT-X, 5HT7, HTR7

Entrez Gene IDs

3363 (Human); 15566 (Mouse); 65032 (Rat)

Gene Symbol

HTR7

UniProt

P34969

Additional 5-HT7 Products

Product Documents for Human 5-HT7 APC-conjugated Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Human 5-HT7 APC-conjugated Antibody

For research use only

Citations
Reviews

Human 5-HT7 APC-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB10325A

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

View all 5-HT7 Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Scientific Data Images for Human 5-HT7 APC-conjugated Antibody

Detection of 5-HT7 in 5-HT7 HEK293/eGFP transfecants vs Irrelevant HEK293/eGFP transfecants by Flow Cytometry

Applications for Human 5-HT7 APC-conjugated Antibody

Flow Cytometry

Spectra Viewer

Plan Your Experiments

Formulation, Preparation, and Storage

Purification

Formulation

Shipping

Stability & Storage

Background: 5-HT7

Long Name

Alternate Names

Entrez Gene IDs

Gene Symbol

UniProt

Additional 5-HT7 Products

Product Documents for Human 5-HT7 APC-conjugated Antibody

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for Human 5-HT7 APC-conjugated Antibody

CONTACT INFORMATION

Stay Connected